Kato Yoji, Suga Naoko
Laboratory of Free Radical and Food Function, School of Human Science and Environment, University of Hyogo, 1-1-12 Shinzaike-honcho, Himeji, Hyogo 670-0092, Japan.
Research Institute of Food and Nutrition, University of Hyogo, 1-1-12 Shinzaike-honcho, Himeji, Hyogo 670-0092, Japan.
J Clin Biochem Nutr. 2018 May;62(3):213-220. doi: 10.3164/jcbn.18-26. Epub 2018 May 1.
There are many chemically reactive compounds, including quinone, in living systems and also food. Even after the ingestion of food polyphenols, quinones derived from catechol moieties could form endogenously in the body. Dopaquinone, dopamine quinone, estrogen-derived quinones, tryptamine-4,5-dione, and ubiquinone are examples of an endogenous quinone. These indicate that quinone is ubiquitously formed or present in living systems and food. Quinones can induce a variety of hazardous effects and also could have beneficial physiological effects. This review focuses on the chemical reactivity of quinone toward a biomolecule and its biological action.
在生物系统以及食物中存在许多化学反应性化合物，包括醌类。即使在摄入食物多酚之后，源自儿茶酚部分的醌类也可在体内内源性形成。多巴醌、多巴胺醌、雌激素衍生的醌类、色胺 - 4,5 - 二酮和泛醌都是内源性醌类的例子。这些表明醌类在生物系统和食物中普遍形成或存在。醌类可诱导多种有害影响，也可能具有有益的生理作用。本综述重点关注醌类对生物分子的化学反应性及其生物学作用。
