Santos Vanessa Ribeiro Dos, Christofaro Diego Giulliano Destro, Gomes Igor Conterato, Júnior Ismael Forte Freitas, Gobbo Luís Alberto
Programa de Pós-Graduação em Ciências da Motricidade, Instituto de Biociências, Universidade Estadual Paulista (UNESP), Rio Claro, SP, Brazil.
Departamento de Educação Física, Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista (UNESP), Presidente Prudente, SP, Brazil.
Rev Bras Ortop. 2017 Sep 22;53(3):300-305. doi: 10.1016/j.rboe.2017.09.002. eCollection 2018 May-Jun.
This study sought to analyze the relationship between the components and aggravations of body composition (obesity, sarcopenia, and sarcopenic obesity) and bone mineral density in elderly subjects aged ≥80 years.
A cross-sectional study design was utilized to assess 128 subjects aged between 80 and 95 years. Body composition and bone mineral density were measured by dual energy X-ray absorptiometry. Gait speed was assessment by walking test. The statistical analyses included Spearman's correlation, one-way analysis of variance, the chi-squared test, and binary logistic regression analysis.
The elderly subjects with sarcopenia had lower bone mineral density compared to the obesity group, with higher risk for presence of osteopenia/osteoporosis in the spine (OR: 2.81; CI: 1.11-7.11) and femur (OR: 2.75; CI: 1.02-7.44). Obesity was shown to be a protective factor for osteopenia/osteoporosis in the spine (OR: 0.43; CI: 0.20-0.93) and femur (OR: 0.27; CI: 0.12-0.62).
It was found that lean mass is more directly related to bone mineral density (total, femur, and spine) and sarcopenia is associated with osteopenia/osteoporosis. Obesity represents a possible protective factor for osteopenia/osteoporosis in elderly subjects aged 80 years and over.
本研究旨在分析80岁及以上老年受试者身体成分（肥胖、肌肉减少症和肌肉减少性肥胖）的组成与加重情况和骨密度之间的关系。
采用横断面研究设计对128名年龄在80至95岁之间的受试者进行评估。通过双能X线吸收法测量身体成分和骨密度。通过步行测试评估步态速度。统计分析包括Spearman相关性分析、单因素方差分析、卡方检验和二元逻辑回归分析。
与肥胖组相比，患有肌肉减少症的老年受试者骨密度较低，脊柱（比值比：2.81；可信区间：1.11 - 7.11）和股骨（比值比：2.75；可信区间：1.02 - 7.44）出现骨质减少/骨质疏松的风险更高。肥胖被证明是脊柱（比值比：0.43；可信区间：0.20 - 0.93）和股骨（比值比：0.27；可信区间：0.12 - 0.62）骨质减少/骨质疏松的保护因素。
发现瘦体重与骨密度（全身、股骨和脊柱）更直接相关，肌肉减少症与骨质减少/骨质疏松有关。肥胖是年龄在80岁及以上老年受试者骨质减少/骨质疏松的一个可能保护因素。
