Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea.
Am J Clin Pathol. 2018 Jul 3;150(2):154-161. doi: 10.1093/ajcp/aqy044.
This study was conducted to establish the Korean national registry, to evaluate the distribution of unexpected antibodies, and to determine the frequencies of specific antigen-negative blood units.
Data added to the Korean national registry between July 2013 and April 2016 were analyzed. The distribution of unexpected antibodies and frequencies of specific antigen-negative blood units were estimated.
In total, 3,513 cases from 22 institutes were registered. The most common single alloantibodies were anti-E, anti-Lea, and anti-M. The most common multiple alloantibodies were anti-E with anti-c, anti-C with anti-e, and anti-Lea with anti-Leb. The frequencies of E-, Lea-, and M-negative units were 42.3%, 56.9%, and 20.2%, respectively.
The distribution of unexpected antibodies and frequencies of specific antigen-negative blood units were investigated using data from the Korean national registry. The results provide useful data to predict the number of blood units to be tested to obtain compatible blood units.
本研究旨在建立韩国国家注册系统，评估意外抗体的分布，并确定特定抗原阴性血液单位的频率。
分析 2013 年 7 月至 2016 年 4 月期间添加到韩国国家注册系统的数据。估计意外抗体的分布和特定抗原阴性血液单位的频率。
共登记了来自 22 个研究所的 3513 例。最常见的单一同种异体抗体是抗-E、抗-Lea 和抗-M。最常见的多种同种异体抗体是抗-E 与抗-c、抗-C 与抗-e 和抗-Lea 与抗-Leb。E-、Lea-和 M-阴性单位的频率分别为 42.3%、56.9%和 20.2%。
使用韩国国家注册系统的数据调查了意外抗体的分布和特定抗原阴性血液单位的频率。结果提供了有用的数据，可以预测需要检测的血液单位数量以获得相容的血液单位。
