Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany.
Texamed GmbH, Ismaning, Germany.
J Eur Acad Dermatol Venereol. 2019 Feb;33(2):384-390. doi: 10.1111/jdv.15123. Epub 2018 Jul 12.
Functional textiles have been proposed as safe adjunct treatment for atopic dermatitis (AD). Some data have been published regarding their antimicrobial properties and their clinical efficacy.
This study examined the physical and functional properties of 11 commercially available functional textiles, including their antimicrobial activity in vitro, as a function of multiple laundering cycles.
All materials were weighed and examined under scanning electron microscopy (SEM) before and after laundering for fibre morphology and silver coating. Bioburden of newly purchased textiles was assessed by measuring bacterial colony forming units (CFU). Deliverable antimicrobial efficacy was evaluated in vitro for each specimen, before and after 30, 70, 100, 150 and 200 laundering cycles.
Textile weight showed high variability. Damaged silver coating of variable degree was observed under SEM in most materials after laundering. Products made of silk showed smoother and tighter fibre morphology compared to cotton. The bacterial load of unwashed material ranged from <1 CFU to 35 CFU per 50 × 50 mm specimen. Most silver-containing products lost their antimicrobial activity rapidly after laundering. Silk and cotton retrieved products had no deliverable antimicrobial effect even in their original state.
Elastic, lightweight textiles with smooth fibres are comfortable for daily use. Functional textiles rapidly losing their deliverable antimicrobial activity in vitro are not advisable for AD patients. Recommendations for functional textiles should be based on a combination of in vitro analysis of products in their original state and after laundering, together with real-life data obtained from controlled clinical trials.
功能性纺织品被提议作为特应性皮炎（AD）的安全辅助治疗。已经有一些关于其抗菌性能和临床疗效的数据发表。
本研究检测了 11 种市售功能性纺织品的物理和功能特性，包括其在多次洗涤循环后的体外抗菌活性。
所有材料在洗涤前后均称重并通过扫描电子显微镜（SEM）检查纤维形态和银涂层。通过测量细菌菌落形成单位（CFU）来评估新购买纺织品的生物负荷。对每个样本进行体外交付抗菌功效评估，分别在 30、70、100、150 和 200 次洗涤循环前后进行。
纺织品重量表现出高度的可变性。在洗涤后，大多数材料的 SEM 观察到银涂层受损程度不同。与棉相比，丝绸制成的产品纤维形态更光滑、更紧密。未经洗涤的材料的细菌负荷范围为<1 CFU 至 35 CFU/50×50mm 标本。大多数含银产品在洗涤后迅速失去抗菌活性。即使在原始状态下，丝绸和棉回收产品也没有交付抗菌作用。
具有弹性、轻便和光滑纤维的功能性纺织品日常使用舒适。在体外迅速失去交付抗菌活性的功能性纺织品不适合 AD 患者。功能性纺织品的建议应基于产品在原始状态和洗涤后的体外分析，并结合从对照临床试验获得的实际数据。
