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用于医疗洗衣去污的银基双功能抗菌洗衣添加剂及织物涂层的研发。

Development of a silver-based dual-function antimicrobial laundry additive and textile coating for the decontamination of healthcare laundry.

作者信息

Owen L, Laird K

机构信息

Infectious Disease Research Group, The Leicester School of Pharmacy, De Montfort University, Leicester, UK.

出版信息

J Appl Microbiol. 2021 Apr;130(4):1012-1022. doi: 10.1111/jam.14850. Epub 2020 Sep 22.

Abstract

AIMS

To repurpose a silver-based antimicrobial textile coating product (Micro-Fresh 1911) as a dual-function antimicrobial laundry additive and textile coating.

METHODS AND RESULTS

Survival of Escherichia coli or Staphylococcus aureus type and clinical isolates in a domestic 40°C wash was assessed with and without soiling and biological detergent. Washing with 2% w/v silver additive (wash phase) reduced E. coli and S. aureus by 7·14-8·08 log and no cross-contamination was observed. Under dirty conditions, 0·5% silver additive in the rinse phase of a wash with biological detergent reduced E. coli and S. aureus by 7·98-8·40 log (0·00-1·42 log cross contamination). BS EN ISO 20645:2004 and BS EN ISO 20743:2013 methods were used to assess the antimicrobial activity of polycotton washed with 2% w/v silver additive against S. aureus and E. coli. The treated polycotton was antimicrobial against E. coli and S. aureus type and clinical isolates and remains active after at least one further wash cycle at 40 or 73°C.

CONCLUSIONS

The silver additive exhibits antimicrobial activity in a 40°C domestic wash, preventing cross contamination onto clean textiles and depositing an antimicrobial coating onto polycotton.

SIGNIFICANCE AND IMPACT OF THE STUDY

The survival of micro-organisms on healthcare uniforms during domestic laundering presents a potential risk of contaminating the home, cross-contamination of other clothing within the wash and transmitting potential pathogens back into healthcare settings via contaminated uniforms. Silver may be useful as an antimicrobial laundry additive to decontaminate healthcare laundry washed at low temperatures in domestic and industrial settings, to therefore reduce the potential risk of transmitting micro-organisms within the domestic and clinical environments.

摘要

目的

将一种银基抗菌织物涂层产品(Micro-Fresh 1911)重新用作双功能抗菌洗衣添加剂和织物涂层。

方法与结果

评估了在有污渍和生物洗涤剂以及无污渍和生物洗涤剂的情况下,大肠杆菌或金黄色葡萄球菌标准菌株及临床分离株在40°C家庭洗涤中的存活情况。使用2%(w/v)银添加剂洗涤(洗涤阶段)可使大肠杆菌和金黄色葡萄球菌减少7.14 - 8.08个对数级,且未观察到交叉污染。在脏污条件下,使用生物洗涤剂洗涤时,漂洗阶段添加0.5%银添加剂可使大肠杆菌和金黄色葡萄球菌减少7.98 - 8.40个对数级(交叉污染为0.00 - 1.42个对数级)。采用BS EN ISO 20645:2004和BS EN ISO 20743:2013方法评估了用2%(w/v)银添加剂洗涤的涤棉对金黄色葡萄球菌和大肠杆菌的抗菌活性。经处理的涤棉对大肠杆菌和金黄色葡萄球菌标准菌株及临床分离株具有抗菌活性,并且在40°C或73°C至少再进行一次洗涤循环后仍保持活性。

结论

银添加剂在40°C家庭洗涤中具有抗菌活性,可防止交叉污染到干净织物上,并在涤棉上沉积抗菌涂层。

研究的意义和影响

微生物在家庭洗涤过程中在医护工作服上的存活存在污染家庭、洗涤过程中其他衣物交叉污染以及通过受污染的工作服将潜在病原体传播回医疗环境的潜在风险。银作为抗菌洗衣添加剂可能有助于对家庭和工业环境中低温洗涤的医护衣物进行去污,从而降低在家庭和临床环境中传播微生物的潜在风险。

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