Al-Mutairi Abdulhakeem, Al-Dhahri Saleh, Mesallam Tamer, Farhat Mohamed, Islam Tahera, Al-Maflehi Nassr, Al-Qahtani Khalid
Department of Otolaryngology Head and Neck Surgery, College of Medicine, AL Qassim University, AL Qassim, Kingdom of Saudi Arabia.
Department of Otolaryngology Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Int J Health Sci (Qassim). 2018 May-Jun;12(3):25-28.
To study the effect of thyroidectomy with totally preserved recurrent laryngeal nerve (RLN) on the objective vocal functions.
It is a prospective pilot study of 10 patients undergoing thyroid surgery on whom to study the effect of thyroidectomy with totally preserved RLN on the objective vocal functions. Patient history and demographic data were collected at the time of admission and in each period of assessment average fundamental frequency; absolute jitter, shimmer, and others were measured. Furthermore, one-way analysis of variance (ANOVA) repeated measurements statistical technique was used to test the difference among the 3 time period of measurements and < 0.05 was considered significant (α = 0.05).
The mean age was 39.5 ± 3.31 years. There were two males and eight females. Total thyroidectomy was performed on eight patients while one had left hemithyroidectomy and one completion thyroidectomy. Histopathology revealed papillary thyroid carcinoma in 50%. 34 acoustic voice analysis parameters were measured using the multidimensional voice program, which showed no significant differences at the end of 1 and 3 month post-operative as compared to the pre-operative measurements. There was no significant difference in measurement for each factor over the time ( > 0.05).
All the acoustic analysis parameters for 10 patients showed no significant differences in 1 and 3 month postoperatively as compared to the pre-operative values. However, due to small sample size, our study may have failed to detect any significant difference.
研究完全保留喉返神经(RLN)的甲状腺切除术对客观嗓音功能的影响。
这是一项针对10例接受甲状腺手术患者的前瞻性初步研究,旨在研究完全保留RLN的甲状腺切除术对客观嗓音功能的影响。在入院时收集患者病史和人口统计学数据,并在每个评估阶段测量平均基频、绝对抖动、闪烁等。此外,采用单向方差分析(ANOVA)重复测量统计技术来检验3个测量时间段之间的差异,P<0.05被认为具有统计学意义(α=0.05)。
平均年龄为39.5±3.31岁。男性2例,女性8例。8例行全甲状腺切除术,1例行左侧甲状腺半切除术,1例行甲状腺次全切除术。组织病理学显示50%为甲状腺乳头状癌。使用多维度嗓音程序测量了34个嗓音分析参数,结果显示术后1个月和3个月时与术前测量值相比无显著差异。各因素测量值随时间无显著差异(P>0.05)。
10例患者的所有嗓音分析参数在术后1个月和3个月时与术前值相比均无显著差异。然而,由于样本量小,我们的研究可能未能检测到任何显著差异。