• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

经右门静脉栓塞后行右半肝切除术治疗的巨大胆管内乳头状肿瘤

A huge intraductal papillary neoplasm of the bile duct treated by right trisectionectomy after right portal vein embolization.

作者信息

Aliyev Vusal, Yasuchika Kentaro, Hammad Ahmed, Tajima Tetsuya, Fukumitsu Ken, Hata Koichiro, Okajima Hideaki, Uemoto Shinji

机构信息

Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Department of Surgery, Mansoura University, Mansoura, Egypt.

出版信息

Ann Hepatobiliary Pancreat Surg. 2018 May;22(2):150-155. doi: 10.14701/ahbps.2018.22.2.150. Epub 2018 May 30.

DOI:10.14701/ahbps.2018.22.2.150
PMID:29896576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5981145/
Abstract

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and recognized precursor of invasive carcinoma. IPNB was detected incidentally in a 60-year-old woman during check up. Radiologic images revealed a huge cystic mass with papillary projection and markedly dilated bile ducts. Biopsies revealed high-grade IPNB. Cholangioscopy detected a connection between the right posterior bile duct and cyst lumen with epithelial dysplasia of the bile duct. Right posterior sectional duct opened in the left hepatic duct. Consequently, right trisectionectomy and extrahepatic bile duct resection were conducted. Histological studies revealed intraductal papillary neoplasm with high-grade intraepithelial neoplasia (carcinoma in situ). IPNB patients without distant metastases are candidates for surgery and complete resection should be conducted to achieve long-term survival.

摘要

胆管内乳头状肿瘤（IPNB）是胆管肿瘤的一种罕见变体，其特征是在胆管腔内呈乳头状生长，是公认的浸润性癌前体。一名60岁女性在体检时偶然发现了IPNB。影像学检查显示一个巨大的囊性肿块，伴有乳头状突起，胆管明显扩张。活检显示为高级别IPNB。胆管镜检查发现右后胆管与囊肿腔之间有连接，胆管存在上皮发育异常。右后段胆管开口于左肝管。因此，进行了右三叶切除术和肝外胆管切除术。组织学研究显示为伴有高级别上皮内瘤变（原位癌）的导管内乳头状肿瘤。无远处转移的IPNB患者是手术的候选对象，应进行完整切除以实现长期生存。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/bc1b762f557e/ahbps-22-150-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/2aefff7a9462/ahbps-22-150-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/c5875bb2623e/ahbps-22-150-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/c6d3a8760def/ahbps-22-150-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/2caa6dced1bc/ahbps-22-150-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/2d702641ba02/ahbps-22-150-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/8442b81aecdb/ahbps-22-150-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/eea689c42157/ahbps-22-150-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/b2043a60fd02/ahbps-22-150-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/be6b5c7e8a13/ahbps-22-150-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/bc1b762f557e/ahbps-22-150-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/2aefff7a9462/ahbps-22-150-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/c5875bb2623e/ahbps-22-150-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/c6d3a8760def/ahbps-22-150-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/2caa6dced1bc/ahbps-22-150-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/2d702641ba02/ahbps-22-150-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/8442b81aecdb/ahbps-22-150-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/eea689c42157/ahbps-22-150-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/b2043a60fd02/ahbps-22-150-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/be6b5c7e8a13/ahbps-22-150-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ba/5981145/bc1b762f557e/ahbps-22-150-g010.jpg

相似文献

1
A huge intraductal papillary neoplasm of the bile duct treated by right trisectionectomy after right portal vein embolization.经右门静脉栓塞后行右半肝切除术治疗的巨大胆管内乳头状肿瘤
Ann Hepatobiliary Pancreat Surg. 2018 May;22(2):150-155. doi: 10.14701/ahbps.2018.22.2.150. Epub 2018 May 30.
2
Recurrent intraductal papillary neoplasm of the bile duct due to intraductal dissemination: a case report and literature review.导管内播散所致复发性胆管内乳头状肿瘤：1例报告并文献复习
Surg Case Rep. 2021 Nov 5;7(1):238. doi: 10.1186/s40792-021-01318-0.
3
Planned limited resection of the extrahepatic bile duct in a case of intraductal papillary neoplasm of the bile duct based on preoperative examinations.基于术前检查，对胆管内乳头状肿瘤病例行计划性肝外胆管局限性切除术。
Clin J Gastroenterol. 2020 Apr;13(2):233-239. doi: 10.1007/s12328-019-01049-8. Epub 2019 Oct 9.
4
Intraductal papillary neoplasm of the bile duct: Assessment of invasive carcinoma and long-term outcomes using MRI.胆管内乳头状肿瘤：应用 MRI 评估浸润性癌和长期预后。
J Hepatol. 2019 Apr;70(4):692-699. doi: 10.1016/j.jhep.2018.12.005. Epub 2018 Dec 14.
5
Branch-type intraductal papillary neoplasm of the bile duct treated with laparoscopic anatomical resection: a case report.腹腔镜解剖性切除治疗胆管分支型导管内乳头状肿瘤：一例报告
Surg Case Rep. 2020 May 15;6(1):103. doi: 10.1186/s40792-020-00864-3.
6
Spread of Intraductal Papillary Neoplasm Arising from the Cystic Duct of the Biliary Tree.起源于胆管系统胆囊管的导管内乳头状肿瘤的扩散
Case Rep Gastroenterol. 2016 May 19;10(1):7-16. doi: 10.1159/000442707. eCollection 2016 Jan-Apr.
7
Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct.胆管内乳头状肿瘤的诊断与治疗现状
World J Gastroenterol. 2021 Apr 21;27(15):1569-1577. doi: 10.3748/wjg.v27.i15.1569.
8
Long-term observation and treatment of a widespread intraductal papillary neoplasm of the bile duct extending from the intrapancreatic bile duct to the bilateral intrahepatic bile duct: A case report.一例从胰内胆管延伸至双侧肝内胆管的广泛胆管内乳头状瘤的长期观察与治疗：病例报告
Int J Surg Case Rep. 2017;38:166-171. doi: 10.1016/j.ijscr.2017.07.031. Epub 2017 Jul 23.
9
A huge intraductal papillary mucinous carcinoma of the bile duct treated by right trisectionectomy with caudate lobectomy.右三叶切除术联合尾状叶切除术治疗胆管巨大的腔内乳头状黏液性癌。
World J Surg Oncol. 2009 Dec 5;7:93. doi: 10.1186/1477-7819-7-93.
10
Intraductal papillary neoplasms of the bile duct.胆管内乳头状肿瘤
Int J Hepatol. 2014;2014:459091. doi: 10.1155/2014/459091. Epub 2014 May 18.

引用本文的文献

1
Intraductal Papillary Neoplasms of the Bile Duct: Clinical Case Insights and Literature Review.胆管内乳头状肿瘤：临床病例见解与文献综述
Clin Pract. 2024 Aug 27;14(5):1669-1681. doi: 10.3390/clinpract14050133.
2
Surgical Treatment of Intraductal Papillary Neoplasm of the Bile Duct: A Report of Two Cases and Review of the Literature.胆管内乳头状肿瘤的外科治疗：两例报告并文献复习
Front Oncol. 2022 Jun 23;12:916457. doi: 10.3389/fonc.2022.916457. eCollection 2022.

本文引用的文献

1
Long-term observation and treatment of a widespread intraductal papillary neoplasm of the bile duct extending from the intrapancreatic bile duct to the bilateral intrahepatic bile duct: A case report.一例从胰内胆管延伸至双侧肝内胆管的广泛胆管内乳头状瘤的长期观察与治疗：病例报告
Int J Surg Case Rep. 2017;38:166-171. doi: 10.1016/j.ijscr.2017.07.031. Epub 2017 Jul 23.
2
Intraductal papillary neoplasm of the bile ducts: A case report and literature review.胆管内乳头状肿瘤：一例报告及文献复习
World J Gastroenterol. 2015 Nov 21;21(43):12498-504. doi: 10.3748/wjg.v21.i43.12498.
3
Multicentric recurrence of intraductal papillary neoplasms of bile duct in the remnant intrahepatic bile duct after curative resection.
根治性切除术后肝内残留胆管中胆管导管内乳头状肿瘤的多中心复发
Int J Surg Case Rep. 2015;12:123-7. doi: 10.1016/j.ijscr.2015.05.033. Epub 2015 May 30.
4
Intraductal papillary neoplasms of the bile duct.胆管内乳头状肿瘤
Int J Hepatol. 2014;2014:459091. doi: 10.1155/2014/459091. Epub 2014 May 18.
5
Intraductal papillary neoplasm of the bile duct.胆管内乳头状肿瘤。
World J Gastroenterol. 2013 Dec 14;19(46):8595-604. doi: 10.3748/wjg.v19.i46.8595.
6
Clinicopathological features and prognosis of mucin-producing bile duct tumor and mucinous cystic tumor of the liver: a multi-institutional study by the Japan Biliary Association.肝产黏液胆管肿瘤和黏液性囊性肿瘤的临床病理特征及预后：日本胆道协会的多机构研究
J Hepatobiliary Pancreat Sci. 2014 Mar;21(3):176-85. doi: 10.1002/jhbp.23. Epub 2013 Aug 1.
7
Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.胆管内乳头状肿瘤：逐步进展为癌涉及共同的分子途径。
Mod Pathol. 2014 Jan;27(1):73-86. doi: 10.1038/modpathol.2013.112. Epub 2013 Jul 5.
8
Clinicopathologic features of intraductal papillary neoplasm of the bile duct according to histologic subtype.根据组织学亚型分析胆管内乳头状肿瘤的临床病理特征。
Am J Gastroenterol. 2012 Jan;107(1):118-25. doi: 10.1038/ajg.2011.316. Epub 2011 Sep 27.
9
Similarities and differences between intraductal papillary tumors of the bile duct with and without macroscopically visible mucin secretion.胆管内乳头状肿瘤伴和不伴肉眼可见黏液分泌的异同。
Am J Surg Pathol. 2011 Apr;35(4):512-21. doi: 10.1097/PAS.0b013e3182103f36.
10
Usefulness of peroral cholangioscopy in preoperative diagnosis of intraductal papillary neoplasm of the bile duct.经口胆管镜检查在胆管内乳头状肿瘤术前诊断中的应用价值
Hepatogastroenterology. 2010 Jul-Aug;57(101):691-3.