van Seters A P, Bots G T, van Dulken H, Luyendijk W, Vielvoye G J
Neurosurgery. 1985 Jun;16(6):813-7. doi: 10.1227/00006123-198506000-00014.
The treatment of a slowly growing invasive prolactinoma with bromocriptine for 8 months resulted in a substantial decrease in plasma prolactin levels despite rapid suprasellar tumor expansion. On exploration, this uncommon observation could be attributed to hematogenous metastasis from an occult gastric adenocarcinoma to the pituitary tumor. Apart from infiltration of neighboring parts of the hypothalamus, autopsy revealed no other hematogenous metastases. This extraordinary type of neoplasm-to-neoplasm metastasis was not shown by computed tomography. This possibility should be considered whenever progressive growth of a pituitary mass is accompanied by a decrease in hormonal overproduction.
用溴隐亭治疗缓慢生长的侵袭性催乳素瘤8个月，尽管鞍上肿瘤迅速扩大，但血浆催乳素水平仍大幅下降。经检查，这一罕见观察结果可归因于隐匿性胃腺癌经血行转移至垂体肿瘤。尸检发现，除下丘脑邻近部位受浸润外，未发现其他血行转移。计算机断层扫描未显示这种肿瘤间转移的特殊类型。每当垂体肿块进行性生长并伴有激素过度分泌减少时，都应考虑这种可能性。
