Galle Fernando Alexis, Martella Diana, Bresciani Guilherme
Facultad de Ciencias de la Educación, Universidad San Sebastián, Puerto Montt, Chile; Universidad Autónoma de Chile, Chile.
Universidad Autónoma de Chile, Chile.
Rev Esp Geriatr Gerontol. 2018 Sep-Oct;53(5):279-284. doi: 10.1016/j.regg.2018.03.003. Epub 2018 Jun 10.
Aging is characterised by a gradual loss of the functional reserve. This, along with the fostering of sedentary habits and the increase in risk factors, causes a deterioration of antioxidant defences and an increase of the circulatory levels of inflammatory and oxidative markers, boosting a low-rate chronic inflammation, defined as inflamm-aging. This phenomenon is present in the aetiopathology of chronic diseases, as well as in cognitive deterioration cases associated with aging. The objective of this review is to describe the modulation of antioxidant and anti-inflammatory effects of physical exercise of moderate intensity and volume in the elderly. Evidence of its effectiveness as a non-pharmacological resource is presented, which decreases some deleterious effects of aging. This is mainly due to its neuroprotective action, the increase in circulating anti-inflammatory markers, and the improvement of antioxidant defence derived from its practice.
衰老的特征是功能储备逐渐丧失。这与久坐习惯的养成以及风险因素的增加一起，导致抗氧化防御能力下降，炎症和氧化标志物的循环水平升高，从而引发一种低水平的慢性炎症，即炎症衰老。这种现象存在于慢性疾病的病因病理中，也存在于与衰老相关的认知衰退病例中。本综述的目的是描述中等强度和运动量的体育锻炼对老年人抗氧化和抗炎作用的调节。文中展示了其作为一种非药物资源有效性的证据，它能减少衰老的一些有害影响。这主要归因于其神经保护作用、循环抗炎标志物的增加以及因锻炼而改善的抗氧化防御能力。
