Department of Molecular Biology and Genetics, İzmir International Biomedicine and Genome Institute, Dokuz Eylül University, Balçova, 35340 İzmir, Turkey.
Department of Pharmacology, Ege University, Institute of Health Sciences, Bornova, 35040 İzmir, Turkey.
Sensors (Basel). 2018 Jun 13;18(6):1924. doi: 10.3390/s18061924.
Novel sensitive, rapid and economical biosensors are being developed in a wide range of medical environmental and food applications. In this paper, we review some of the main advances in the field over the past few years by discussing recent studies from literature. A biosensor, which is defined as an analytical device consisting of a biomolecule, a transducer and an output system, can be categorized according to the type of the incorporated biomolecule. The biomolecules can be enzymes, antibodies, ssDNA, organelles, cells etc. The main biosensor categories classified according to the biomolecules are enzymatic biosensors, immunosensors and DNA-based biosensors. These sensors can measure analytes produced or reduced during reactions at lower costs compared to the conventional detection techniques. Numerous types of biosensor studies conducted over the last decade have been explored here to reveal their key applications in medical, environmental and food industries which provide comprehensive perspective to the readers. Overviews of the working principles and applications of the reviewed sensors are also summarized.
新型敏感、快速且经济的生物传感器正在医学、环境和食品等多个领域得到广泛开发。本文通过讨论近年来文献中的研究进展,综述了过去几年该领域的主要进展。生物传感器是由生物分子、换能器和输出系统组成的分析装置,可以根据所包含的生物分子的类型进行分类。生物分子可以是酶、抗体、单链 DNA、细胞器、细胞等。根据生物分子分类的主要生物传感器类别是酶生物传感器、免疫传感器和基于 DNA 的生物传感器。与传统检测技术相比,这些传感器可以以更低的成本测量反应过程中产生或减少的分析物。本文探讨了过去十年中进行的多种类型的生物传感器研究,以揭示它们在医学、环境和食品工业中的关键应用,为读者提供全面的视角。还总结了所综述传感器的工作原理和应用概述。