Pusateri Antoinette J, Krishna Somashekar G
Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Diseases. 2018 Jun 13;6(2):50. doi: 10.3390/diseases6020050.
Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer. Pancreatic cystic lesions (PCLs) with malignant potential include: mucinous PCLs (intraductal papillary mucinous neoplasms and mucinous cystic neoplasm), solid pseudopapillary tumors and cystic neuroendocrine tumors. This review summarizes the latest literature describing what is known about the pathogenesis and malignant potential of these PCLs, including unique epidemiological, radiological, histological, genetic and molecular characteristics.
尽管进行了广泛研究，但胰腺癌仍然是最致命的癌症之一。对癌前病变的进一步了解可能会提高治疗和预防胰腺癌的能力。具有恶性潜能的胰腺囊性病变（PCLs）包括：黏液性PCLs（导管内乳头状黏液性肿瘤和黏液性囊性肿瘤）、实性假乳头状肿瘤和囊性神经内分泌肿瘤。本综述总结了描述这些PCLs发病机制和恶性潜能的最新文献，包括独特的流行病学、放射学、组织学、遗传学和分子特征。
