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胰腺病变的内镜超声引导下射频消融术(EUS-RFA)综述

A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions.

作者信息

Karaisz Fred G, Elkelany Osama O, Davies Benjamin, Lozanski Gerard, Krishna Somashekar G

机构信息

Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

出版信息

Diagnostics (Basel). 2023 Feb 1;13(3):536. doi: 10.3390/diagnostics13030536.

Abstract

The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially definitive means to treat pancreatic neuroendocrine tumors and precancerous pancreatic cystic lesions. In addition, EUS-RFA may play a role in the treatment and palliation of non-surgical cases of pancreatic adenocarcinoma. The efficacy of RFA appears to be further enhanced by systemic immunomodulatory effects. Here, we review current studies on the developing role of EUS-RFA in these pancreatic pathologies.

摘要

胰腺切除术相关的发病率限制了有手术切除指征的高危胰腺肿瘤患者的手术选择。内镜超声引导下射频消融术(EUS-RFA)为治疗胰腺神经内分泌肿瘤和癌前胰腺囊性病变提供了一种微创且可能具有确定性的方法。此外,EUS-RFA可能在胰腺腺癌非手术病例的治疗和姑息治疗中发挥作用。射频消融的疗效似乎因全身免疫调节作用而进一步增强。在此,我们综述了当前关于EUS-RFA在这些胰腺疾病中不断发展的作用的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a01/9914142/d1c4265c4d8a/diagnostics-13-00536-g001.jpg

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