Makuuchi M, Sukigara M, Mori T, Kobayashi J, Yamazaki S, Hasegawa H, Moriyama N, Takayasu K, Hirohashi S
Radiology. 1985 Aug;156(2):331-4. doi: 10.1148/radiology.156.2.2989972.
Bile duct necrosis because of transcatheter hepatic arterial embolization (THAE) in two patients with hepatocellular carcinoma is reported. Preoperative THAE was performed on 29 patients, and bile duct necrosis was experienced by two of the 29 (7%). In these two patients, gelatin (Gelfoam) powder was used as the embolus. Among the 24 whose embolus was clear, four were embolized with gelatin powder. Therefore, incidence of bile duct necrosis after THAE with gelatin powder was 50%. Because of the hazards of severe complications such as bile duct necrosis, we conclude that gelatin powder should not be used except for the THAE of no more than one segment of the liver.
报告了2例肝细胞癌患者因经导管肝动脉栓塞术(THAE)导致胆管坏死的情况。对29例患者进行了术前THAE,其中29例中有2例(7%)发生了胆管坏死。在这2例患者中,使用明胶(Gelfoam)粉作为栓塞剂。在栓塞剂明确的24例患者中,有4例使用明胶粉进行栓塞。因此,使用明胶粉进行THAE后胆管坏死的发生率为50%。由于胆管坏死等严重并发症的风险,我们得出结论,除了对肝脏不超过一个肝段进行THAE外,不应使用明胶粉。