Alm Tove, Lundberg Emma, Uhlén Mathias
Royal Institute of Technology (KTH), Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden.
EuPA Open Proteom. 2016 Jan 7;10:56-58. doi: 10.1016/j.euprot.2016.01.002. eCollection 2016 Mar.
The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this public⿿private partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniques (such as siRNA or CRISPR) have been used to verify antibody binding. The initiative is launched under the aegis of Antibodypedia, a database designed to allow comparisons and scoring of publicly available antibodies towards human protein targets. What is known about an antibody is the foundation of the scoring and ranking system in Antibodypedia.
新发起的“亲和结合物敲低计划”鼓励抗体供应商和用户加入这一公私合作项目，该项目利用众包方式收集抗体的表征数据。研究人员被要求分享来自使用基因编辑技术（如小干扰RNA或CRISPR）验证抗体结合的实验的验证数据。该计划是在Antibodypedia的支持下发起的，Antibodypedia是一个旨在对针对人类蛋白质靶点的公开可用抗体进行比较和评分的数据库。关于抗体的已知信息是Antibodypedia评分和排名系统的基础。
