Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Institute for Research Initiatives, Nara Institute of Science and Technology, 8916-5, Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Macromol Rapid Commun. 2018 Aug;39(15):e1800239. doi: 10.1002/marc.201800239. Epub 2018 Jun 13.
In order to prepare thermoresponsive polyurethane gels, a novel polyurethane bearing oligo(ethylene glycol) (OEG) as the side chain is successfully synthesized with hexamethylene diisocyanate and OEG tartrate ester. The aqueous solution of the polyurethane shows sharp and clear lower critical solution temperature behavior at 34 °C. Furthermore, a hydrogel based on the same polyurethane is also successfully prepared using glycerol as the crosslinker. This polyurethane hydrogel including 10 mol% of glycerol presents a large swelling ratio change between 4 °C and 37 °C from 250% to 40%.
为了制备温敏型聚氨酯凝胶，成功地合成了一种新型的带有聚乙二醇（OEG）侧链的聚氨酯，其原料为己二异氰酸酯和 OEG 酒石酸酯。该聚氨酯在水溶液中表现出明显的、清晰的下临界溶液温度行为，温度在 34°C。此外，还成功地使用甘油作为交联剂制备了基于相同聚氨酯的水凝胶。这种含有 10 mol%甘油的聚氨酯水凝胶在 4°C 和 37°C 之间的溶胀比变化很大，从 250%增加到 40%。
