Liu Dandan, Sun Jing
Key Laboratory of Biobased Polymer Materials, Shandong Provincial Education Department, School of Polymer Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Polymers (Basel). 2020 Dec 12;12(12):2973. doi: 10.3390/polym12122973.
Stimuli-responsive polymers have been widely studied in many applications such as biomedicine, nanotechnology, and catalysis. Temperature is one of the most commonly used external triggers, which can be highly controlled with excellent reversibility. Thermoresponsive polymers exhibiting a reversible phase transition in a controlled manner to temperature are a promising class of smart polymers that have been widely studied. The phase transition behavior can be tuned by polymer architectures, chain-end, and various functional groups. Particularly, thermoresponsive polypeptoid is a type of promising material that has drawn growing interest because of its excellent biocompatibility, biodegradability, and bioactivity. This paper summarizes the recent advances of thermoresponsive polypeptoids, including the synthetic methods and functional groups as well as their applications.
刺激响应性聚合物已在生物医学、纳米技术和催化等许多应用中得到广泛研究。温度是最常用的外部触发因素之一，其具有高度可控性且可逆性极佳。以可控方式对温度表现出可逆相变的热响应性聚合物是一类备受关注的智能聚合物，已得到广泛研究。相变行为可通过聚合物结构、链端和各种官能团进行调节。特别地，热响应性聚肽是一种很有前景的材料，因其具有优异的生物相容性、生物降解性和生物活性而越来越受到关注。本文综述了热响应性聚肽的最新进展，包括合成方法、官能团及其应用。
