Haas O, Schwarzmeier J D, Paietta E, Nacheva E, Fischer P
Acta Med Austriaca. 1979;6(5):229-31.
This report deals with a new syndrome characterized by refractory anemia, an aberration of chromosome 5 (deletion of the long arm) and the subsequent appearance of acute myeloid leukemia. The results stress the importance of chromosomal studies in cases of unclear, long-lasting and therapy-resistant anemia, since they may allow the early recognition of the development of acute leukemia.
本报告涉及一种以难治性贫血、5号染色体畸变(长臂缺失)以及随后出现急性髓系白血病为特征的新综合征。研究结果强调了染色体研究在不明原因、持续时间长且对治疗耐药的贫血病例中的重要性,因为这可能有助于早期识别急性白血病的发展。