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基于有限元的三维计算机建模用于马蹄内翻足畸形的个性化治疗规划:病例报告及技术描述

Finite-element-based 3D computer modeling for personalized treatment planning in clubfoot deformity: Case report with technique description.

作者信息

Gozar Horea, Derzsi Zoltan, Chira Alexandru, Nagy Örs, Benedek Theodora

机构信息

Clinic of Pediatric Surgery and Orthopedics, University of Medicine and Pharmacy Tirgu Mures Laboratory of Advanced Research in Multimodality Imaging, University of Medicine and Pharmacy Department of Structural Mechanics, Faculty of Civil Engineering, Technical University of Cluj-Napoca Discipline of Orthopedics I, University of Medicine and Pharmacy Tirgu Mures, Romania.

出版信息

Medicine (Baltimore). 2018 Jun;97(24):e11021. doi: 10.1097/MD.0000000000011021.

Abstract

RATIONALE

In clubfoot deformity, planning of corrective treatment requires a complex understanding of the foot anatomy, as well as of the geometry and distribution of altered mechanical forces acting at the level of the deformed foot. At the same time, treatment success depends largely on the selection of the most appropriate shape and angles of the customized orthesis developed for foot correction. Therefore, a complex assessment of the intensity and distribution of the mechanical forces at this site is mandatory prior to initiation of any corrective therapy.

PATIENT CONCERNS

We present here the case of a 3-year-old male child with clubfoot deformity, weighting 20 kg, with no other congenital malformations, in whom finite element modeling (FEM) technology associated with a newly developed technique of three-dimensional (3D) computational simulation was applied for personalized treatment planning.

INTERVENTIONS

The FEM-based computational 3D simulation technique allowed selection of the corrective treatment associated with the most physiologic pattern of force distribution at the level of the foot.

OUTCOMES

The proposed technique led to selection of the most appropriate therapy that successfully corrected the foot deformity. After 3D computer simulations, the elongations recorded were 2.71 cm for Achilles tendon, 1.69 cm for anterior tibialis tendon, 1.35 cm for the long flexor of the toes, and 1.69 cm for the long flexor of the hallux. The Von Mises equivalent stress distribution was σ = 4.26 MPa, not exceeding the elastic capacity of the bones, therefore the residual deformations were minimal. The customized treatment selected in this way was highly appropriate for the child, and led to complete recovery of the deformity in three months.

LESSONS

This case is the first one in which FEM-based computational 3D modeling was applied for selection of treatment strategy in a child with clubfoot. The case reported here illustrates the role of advanced medical computer technology, based on complex image processing, FEM and 3D simulations, in providing an effective clinical decision support tool for personalized treatment selection in children with clubfoot deformity.

摘要

原理

在马蹄内翻足畸形中,矫正治疗方案的制定需要对足部解剖结构有深入理解,同时要了解作用于畸形足部的改变的力学力的几何形状和分布。与此同时,治疗的成功很大程度上取决于为足部矫正定制的矫形器最合适的形状和角度的选择。因此,在开始任何矫正治疗之前,必须对该部位的力学力的强度和分布进行综合评估。

患者情况

我们在此展示一名3岁男童马蹄内翻足畸形的病例,体重20千克,无其他先天性畸形,在该病例中,将有限元建模(FEM)技术与新开发的三维(3D)计算模拟技术相结合,用于个性化治疗方案的制定。

干预措施

基于有限元的计算3D模拟技术能够选择与足部水平最生理的力分布模式相关的矫正治疗方法。

结果

所提出的技术导致选择了最适当的治疗方法,成功矫正了足部畸形。经过3D计算机模拟,记录的跟腱伸长为2.71厘米,胫前肌腱伸长为1.69厘米,趾长屈肌伸长为1.35厘米,拇长屈肌伸长为1.69厘米。冯·米塞斯等效应力分布为σ = 4.26兆帕,未超过骨骼的弹性能力,因此残余变形最小。以这种方式选择的定制治疗方法非常适合该儿童,并在三个月内使畸形完全恢复。

经验教训

该病例是首次将基于有限元的计算3D建模应用于马蹄内翻足儿童治疗策略的选择。此处报告的病例说明了基于复杂图像处理、有限元和3D模拟的先进医学计算机技术在为马蹄内翻足畸形儿童的个性化治疗选择提供有效的临床决策支持工具方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/650b/6024088/5a01b6befc66/medi-97-e11021-g001.jpg

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