Falkay G, Kovács L
Acta Physiol Hung. 1985;65(4):491-5.
The binding characteristics of the beta-adrenergic ligand [3H]-dihydroalprenolol (DHA) were determined in particulate membranes of early and term human placenta and myometrium. Human placenta is rich in beta adrenergic receptors and the binding capacity increases with increasing gestation. There was no difference in receptor density in human myometrium comparing the first trimester and term. Binding of DHA to human myometrial beta-adrenergic receptors provides a tool for the analysis of beta-adrenergic agents as potentially useful tocolytic agents.
在早期和足月妊娠的人胎盘及子宫肌层的微粒体膜中测定了β-肾上腺素能配体[3H]-二氢烯丙洛尔（DHA）的结合特性。人胎盘富含β-肾上腺素能受体，且结合能力随孕周增加而增强。比较孕早期和足月时，人子宫肌层的受体密度没有差异。DHA与人子宫肌层β-肾上腺素能受体的结合为分析β-肾上腺素能药物作为潜在有用的宫缩抑制剂提供了一种工具。
