一项关于年轻男性铜吸收的稳定同位素研究：植酸盐和α-纤维素的影响。

A stable isotope study of copper absorption in young men: effect of phytate and alpha-cellulose.

作者信息

Turnlund J R, King J C, Gong B, Keyes W R, Michel M C

出版信息

Am J Clin Nutr. 1985 Jul;42(1):18-23. doi: 10.1093/ajcn/42.1.18.

DOI:10.1093/ajcn/42.1.18

Abstract

A sixty-three day study was conducted with young men confined to a metabolic unit to study the effects of alpha-cellulose and phytate on copper absorption. Copper absorption was determined with 65Cu, a stable isotope of copper, during each of 3 dietary treatments (basal diet, basal diet + alpha-cellulose, or basal diet + phytate). The addition of alpha-cellulose or phytate to the basal diet did not affect copper absorption. Average copper absorption was 35.0% from the basal diet, 34.1% from the diet with 0.5 g alpha-cellulose per kg body weight added, and 31.4% from the diet with 2.34 g of phytate as sodium phytate added to the diet. Copper absorption was significantly different between subjects and averaged 44.1%, 26.8%, 33.4%, and 29.5% in individual subjects. The results suggest that high levels of either alpha-cellulose or phytate do not have marked effects on copper absorption, but copper absorption differs between individuals.

摘要

对被限制在代谢单元中的年轻男性进行了一项为期63天的研究，以研究α-纤维素和植酸盐对铜吸收的影响。在三种饮食处理（基础饮食、基础饮食+α-纤维素或基础饮食+植酸盐）的每一种期间，用铜的稳定同位素65Cu测定铜吸收。在基础饮食中添加α-纤维素或植酸盐不影响铜吸收。基础饮食的平均铜吸收为35.0%，添加每千克体重0.5克α-纤维素的饮食为34.1%，添加2.34克植酸钠作为植酸盐的饮食为31.4%。个体之间的铜吸收存在显著差异，个体受试者的平均铜吸收分别为44.1%、26.8%、33.4%和29.5%。结果表明，高水平的α-纤维素或植酸盐对铜吸收没有显著影响，但个体之间的铜吸收存在差异。