Ma W Y, Liu W, Li X Z, Ye P, Zhang L Q, Cai X L
Department of Dermatology, Qilu Hospital of Shandong University, Jinan 250012, China.
Department of Otorhinolaryngology, Northern Region, Central Hospital of Shandong Zibo, Zibo 255031, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jun 7;53(6):440-443. doi: 10.3760/cma.j.issn.1673-0860.2018.06.010.
To discuss the application of Mohs microsurgery in nasal and facial basal cell carcinoma (BCC) and analyze the pathological and clinical features. The clinical data of 127 patients who were diagnosed by pathology as nasal and facial BCC in Qilu Hospital of Shandong University from January 2010 to January 2015 were retrospectively analysed. The value of Mohs microsurgery was discussed and the nasal & facial sites of BCC lesions, clinical and histopathology features were summarized. The proportion of male and female was 1.27︰1 in 127 patients, the ages ranged from 27 to 91 years. The top three inflicted area in nasal and facial was followed by nasal dorsum, nasal root and upper lip.The most frequent clinical type was nodular ulcerative type.The most common pathological type was nodular and pigmented. Routine surgical resection was performed in 62 cases (48.8%) while Mohs micrographic surgery in 38 cases (29.9%). Follow-up duration was 37 months on average. Local recurrence occurred in 5 cases in routine surgical resection group while there was no recurrence in Mohs micrographic surgery group. There was no distant metastasis in all cases. There are few specific clinical manifestation in nasal & facial BCC. Surgical treatment is prefered, especially by Mohs micrographic surgery, because it can strictly control the scope of surgical resection and obtain malformation repairment as well as beauty in nasal and facial region.
探讨莫氏显微外科手术在鼻面部基底细胞癌(BCC)中的应用,并分析其病理及临床特征。回顾性分析2010年1月至2015年1月在山东大学齐鲁医院经病理诊断为鼻面部BCC的127例患者的临床资料。讨论莫氏显微外科手术的价值,总结鼻面部BCC病变部位、临床及组织病理学特征。127例患者中男女比例为1.27∶1,年龄范围为27至91岁。鼻面部受累部位前三位依次为鼻背、鼻根和上唇。最常见的临床类型为结节溃疡性。最常见的病理类型为结节型和色素型。62例(48.8%)行常规手术切除,38例(29.9%)行莫氏显微外科手术。平均随访时间为37个月。常规手术切除组有5例局部复发,而莫氏显微外科手术组无复发。所有病例均无远处转移。鼻面部BCC鲜有特异性临床表现。手术治疗为宜,尤其是莫氏显微外科手术,因其能严格控制手术切除范围,并实现鼻面部畸形修复及美观。