Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu, Sichuan, 611130, People's Republic of China.
Cheng Du Hua Luo Bio-Tech Col., Ltd, Chengdu, Sichuan, 610062, People's Republic of China.
Lipids Health Dis. 2018 Jun 15;17(1):139. doi: 10.1186/s12944-018-0788-3.
The aim of this study was to determine the effects of plant essential oil supplementation on growth performance, immune function and antioxidant activities in weaned pigs.
In the study, 24 weaned pigs were used to explore the effects of plant essential oil (PEO) on growth performance, immune properties and antioxidant activities. Pigs were fed with a basal diet (CON) or basal diet containing different concentrations of PEO (PEO50: 50 ppm; PEO100: 100 ppm; PEO200: 200 ppm). After 3 weeks, all pigs were slaughtered and blood and tissue samples were collected for biochemical analysis.
The results showed that PEO supplementation quadratically increased body weight gain (BWG) (P = 0.031), linearly (P < 0.05) and quadratically (P < 0.05) decreased F:G. In addition, IgG increased linearly (P < 0.05) and IgM increased linearly (P < 0.05) and quadratically (P < 0.05) as PEO supplementation. Similarly, MDA in serum, jejunal mucosa and pancreas were linearly decreased (P < 0.05) and GSH in serum (linear and quadratic, P < 0.05), duodenal mucosa (linear and quadratic, P < 0.05) and in ileal mucosa (linear and quadratic, P < 0.05) were notably increased. Futhermore, antioxidant-related genes expression levels of GST in spleen (linear and quadratic, P < 0.05), GPX1 (quadratic, P < 0.05) and SOD1 (linear, P < 0.05) in spleen and GST in liver (quadratic, P < 0.05) were markedly upregulated by PEO supplementation increasing.
These results suggest that PEO improves growth performance, immune function, and antioxidant activities in weaned pigs, and it may also relieve weaning stress if used as a feed additive in the livestock industry. And that supplementation 200 ppm PEO in diet would seem to be economically feasible.
本研究旨在确定植物精油（PEO）对断奶仔猪生长性能、免疫功能和抗氧化活性的影响。
本研究采用 24 头断奶仔猪，研究 PEO 对生长性能、免疫特性和抗氧化活性的影响。仔猪饲喂基础日粮（CON）或基础日粮添加不同浓度 PEO（PEO50：50ppm；PEO100：100ppm；PEO200：200ppm）。3 周后，所有仔猪均进行屠宰，采集血液和组织样品进行生化分析。
结果表明，PEO 补充量呈二次增加体重增加（BWG）（P=0.031），线性（P<0.05）和二次（P<0.05）降低 F：G。此外，IgG 线性增加（P<0.05），IgM 线性增加（P<0.05）和二次增加（P<0.05）。同样，血清、空肠黏膜和胰腺 MDA 线性降低（P<0.05），血清 GSH（线性和二次，P<0.05）、十二指肠黏膜（线性和二次，P<0.05）和回肠黏膜（线性和二次，P<0.05）显著增加。此外，脾 GST 的抗氧化相关基因表达水平（线性和二次，P<0.05）、GPX1（二次，P<0.05）和 SOD1（线性，P<0.05）和肝 GST（二次，P<0.05）显著上调。
这些结果表明，PEO 可改善断奶仔猪的生长性能、免疫功能和抗氧化活性，如果作为饲料添加剂在畜牧业中使用，还可能缓解断奶应激。在日粮中添加 200ppm PEO 似乎在经济上是可行的。
