[2010 - 2012年中国农村老年居民的血清视黄醇浓度] - Suppr

Chen Jing, Hu Yichun, Yang Chun, Yun Chunfeng, Wang Rui, Mao Deqian, Li Weidong, Yang Yanhua, Piao Jianhua, Yang Lichen, Yang Xiaoguang

Key Laboratory of Trace Element Nutrition of National Health and Family Planning Commission, National Institute for Nutrition and Health, Chinese Center for Disease Center and Prevention, Beijing 100050, China.

Wei Sheng Yan Jiu. 2017 May;46(3):356-360.

OBJECTIVE

To assess the vitamin A status of Chinese rural elderly population by analyzing the serum retinol levels of Chinese rural elderly residents in 2010-2012.

METHODS

Data were from the Chinese National Nutrition and Health Survey in2010-2012. Using the multistage stratified cluster sampling method, serum samples from the elderly residents aged above 60 years old( including), were obtained from 45 general rural and 30 poor rural. The basic situation of the survey object was collected by the questionnaire survey. The concentration of serum retinol was determined by high performance liquid chromatography( HPLC). The vitamin A deficiency( VAD) was judged by the related standard recommended by WHO. A total of 2 413 elderly residents were included in the study. The levels of serum retinol and the prevalence of vitamin A deficiency and marginal vitamin A deficiency were also compared.

RESULTS

The level of serum retinol for rural elderly residents was 1. 88( 1. 45-2. 45) μmol/L. The serum retinol level of poor rural resident was( 1. 92( 1. 46-2. 48) μmol/L), which was significant for the ordinary rural residents( 1. 86( 1. 44-2. 41) μmol/L)( χ~~2= 5. 1428, P = 0. 0233). The serum retinol of male elderly( 1. 97( 1. 48-2. 54)) was statistically higher than female( 1. 82( 1. 42-2. 33))( χ~~2= 22. 3383, P < 0. 0001). The prevalence of VAD among Chinese rural elderly residents was 2. 28%, 2. 79% for ordinary rural residents and 1. 53% for poor rural residents. The marginal VAD rate of Chinese rural elderly residents was 6. 30%, 6. 84% for ordinary rural residents and 5. 51% for poor rural residents. The prevalence of VAD and marginal VAD for male was 2. 18% and5. 57%, respectively. The prevalence of VAD and marginal VAD for female was 2. 38%and 7. 21%, respectively. No statistically difference was observed between different genders. The prevalence of VAD was 1. 93%, 3. 17% and 1. 47% for different age groups( 60 ~ 69, 70 ~ 79 and above 80 years old), and no statistically difference was observed between different age groups. The prevalence of marginal VAD was 5. 87%, 6. 20% and 11. 74% for different age groups, and statistically difference was observed between different age groups( χ~2= 7. 3858, P = 0. 039).

CONCLUSION

Chinese rural elderly population has a certain degree of vitamin A deficiency and marginal deficiency, the marginal deficiency of the elderly over 80 years old is more common.

目的

通过分析2010 - 2012年中国农村老年居民的血清视黄醇水平，评估中国农村老年人群的维生素A状况。

方法

数据来自2010 - 2012年中国国家营养与健康调查。采用多阶段分层整群抽样方法，从45个一般农村和30个贫困农村中抽取60岁及以上老年居民的血清样本。通过问卷调查收集调查对象的基本情况。采用高效液相色谱法（HPLC）测定血清视黄醇浓度。根据世界卫生组织推荐的相关标准判断维生素A缺乏（VAD）情况。本研究共纳入2413名老年居民。同时比较血清视黄醇水平、维生素A缺乏及边缘性维生素A缺乏的患病率。

结果

农村老年居民血清视黄醇水平为1.88（1.45 - 2.45）μmol/L。贫困农村居民血清视黄醇水平为1.92（1.46 - 2.48）μmol/L，显著高于普通农村居民（1.86（1.44 - 2.41）μmol/L）（χ² = 5.1428，P = 0.0233）。老年男性血清视黄醇水平（1.97（1.48 - 2.54））在统计学上高于女性（1.82（1.42 - 2.33））（χ² = 22.3383，P < 0.0001）。中国农村老年居民VAD患病率为2.28%，普通农村居民为2.79%，贫困农村居民为1.53%。中国农村老年居民边缘性VAD率为6.30%，普通农村居民为6.84%，贫困农村居民为5.51%。男性VAD和边缘性VAD患病率分别为2.18%和5.57%。女性VAD和边缘性VAD患病率分别为2.38%和7.21%。不同性别之间未观察到统计学差异。不同年龄组（60～69岁、70～79岁和80岁及以上）VAD患病率分别为1.93%、3.17%和1.47%，不同年龄组之间未观察到统计学差异。不同年龄组边缘性VAD患病率分别为5.87%、6.20%和11.74%，不同年龄组之间观察到统计学差异（χ² = 7.3858，P = 0.039）。