Xiao Sanhua, Luo Lan, Qiao Qian, Lü Xuemin, Wang Yanhui, Feng Lin, Tang Fei, Wang Haiyong, Bie Nana, Wang Yuehong
Institute of Environmental Medicine, MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.
Wei Sheng Yan Jiu. 2017 May;46(3):476-480.
To understand the occurrence and change of mutagencity of water samples in the process of drinking water treatment and distribution in a waterworks taking Yangtze River as its water source in Jiangsu Province.
Large volume of inlet water, finished water and tap water samples were extracted by XAD-2 resin. Mutagencities were assessed by Ames test and a mutation ratio( MR) of 2 or greater was judged as a positive result.
Compared with the samples with S9, samples without S9 presented more positive results( P = 0. 005). That water treatment elevated MR values( P = 0. 007) while the pipe transport made MR values down( P = 0. 038) was observed in samples without S9. The tap water showed weaker mutagenicities than the raw water in samples with S9( P = 0. 008). Compared to the raw water samples, the finished water samples showed more positive results(-S9) and lower MR values( + S9, P =0. 002).
Significant mutagenicities of water samples from the Yangtze Riverand its processed water were presented, and frame shit and direct mutagens deserved special concern.
了解江苏省某以长江为水源的自来水厂在饮用水处理及配水过程中水样致突变性的发生及变化情况。
采用XAD - 2树脂提取大量进水、出厂水和自来水水样。通过艾姆斯试验评估致突变性，突变率（MR）≥2判定为阳性结果。
与加S9的样本相比，不加S9的样本呈现更多阳性结果（P = 0.005）。在不加S9的样本中观察到水处理使MR值升高（P = 0.007），而管道输送使MR值降低（P = 0.038）。加S9的样本中，自来水的致突变性比原水弱（P = 0.008）。与原水样本相比，出厂水样本呈现更多阳性结果（-S9）且MR值更低（+S9，P = 0.002）。
长江及其处理后的水样呈现出显著的致突变性，移码突变和直接致突变物值得特别关注。
