Lv Xuemin, Lu Yi, Yang Xiaoming, Dong Xiaorong, Ma Kunpeng, Xiao Sanhua, Wang Yazhou, Tang Fei
Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
Sci Rep. 2015 Mar 31;5:9572. doi: 10.1038/srep09572.
A total of 54 water samples were collected during three different hydrologic periods (level period, wet period, and dry period) from Plant A and Plant B (a source for Yangtze River and Hanshui River water, respectively), and several water parameters, such as chemical oxygen demand (COD), turbidity, and total organic carbon (TOC), were simultaneously analyzed. The mutagenicity of the water samples was evaluated using the Ames test with Salmonella typhimurium strains TA98 and TA100. According to the results, the organic compounds in the water were largely frame-shift mutagens, as positive results were found for most of the tests using TA98. All of the finished water samples exhibited stronger mutagenicity than the relative raw and distribution water samples, with water samples collected from Plant B presenting stronger mutagenic strength than those from Plant A. The finished water samples from Plant A displayed a seasonal-dependent variation. Water parameters including COD (r = 0.599, P = 0.009), TOC (r = 0.681, P = 0.02), UV254 (r = 0.711, P = 0.001), and total nitrogen (r = 0.570, P = 0.014) exhibited good correlations with mutagenicity (TA98), at 2.0 L/plate, which bolsters the argument of the importance of using mutagenicity as a new parameter to assess the quality of drinking water.
在三个不同水文时期（平水期、丰水期和枯水期），分别从A厂（长江水源）和B厂（汉江水水源）采集了总共54份水样，并同时分析了几个水质参数，如化学需氧量（COD）、浊度和总有机碳（TOC）。使用鼠伤寒沙门氏菌TA98和TA100菌株的艾姆斯试验评估水样的致突变性。结果表明，水中的有机化合物大多为移码诱变剂，因为使用TA98进行的大多数试验都得到了阳性结果。所有出厂水样品的致突变性均强于相对应的原水和配水样品，从B厂采集的水样致突变强度高于A厂采集的水样。A厂的出厂水样品呈现出季节性变化。在每平皿2.0 L的情况下，包括COD（r = 0.599，P = 0.009）、TOC（r = 0.681，P = 0.02）、UV254（r = 0.711，P = 0.001）和总氮（r = 0.570，P = 0.014）在内的水质参数与致突变性（TA98）表现出良好的相关性，这支持了将致突变性作为评估饮用水质量新参数的重要性这一观点。
