Pang Xing, Yu Lugang, Zhou Hui, Lei Ting, Chen Guochong, Qin Liqiang
Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, China.
Wei Sheng Yan Jiu. 2017 Sep;46(5):729-748.
To explore the relationship between abdominal obesity and dyslipidemia in postmenopausal women.
Based on the project of 2014 community comprehensive intervention for prevention of chronic diseases in Suzhou Industrial Park, 2 000 residents in a community were randomly selected. Among them, a total of 323 women with natural menopause for more than 12 months were observed. Height, body weight, waist circumference, blood pressure, and plasma levels of triglycerides( TG) level, total cholesterol( TC) level, high-density lipoprotein cholesterol( HDL-C) level and low-density lipoprotein cholesterol( LDL-C) were measured. Abdominal obesity was diagnosed by waist circumference( ≥85 cm) according to Criteria of Weight for Adults. Hyperglycemia was diagnosed by TG, TC, HDL-C and LDL-C in Guidelines for Prevention and Treatment of Dyslipidemia in Chinese Adults( 2007). Relationship between abdominal obesity and dyslipidemia was analyzed by Logistic regressionmethod.
The incidences of abdominal obesity and dyslipidemia were13. 6%( 44/323) and 29. 7%( 96/323), respectively. The rate of dyslipidemia was significantly higher in abdominal obesity group than in the control group( 43. 2% vs27. 6%, P = 0. 036). Waist circumference was positively correlated with TG( r = 0. 28, P < 0. 01) and LDL-C( r = 0. 20, P < 0. 01), and negatively correlated with HDL-C( r =-0. 26, P < 0. 01). The multivariate Logistic regression analysis showed that abdominal obesity had significantly increased risk of dyslipidemia( OR = 2. 07, 95% CI 1. 04-4. 13, P = 0. 039). The OR for TG and HDL-C were 3. 81( 95% CI 1. 69-8. 60, P =0. 001) and 3. 19( 95% CI 1. 36-7. 52, P = 0. 008), respectively.
Abdominal obesity is likely to be a risk factor for dyslipidemia in postmenopausal women.
探讨绝经后女性腹部肥胖与血脂异常之间的关系。
基于苏州工业园区2014年社区慢性病综合防治项目,随机抽取某社区2000名居民。其中,共观察了323名自然绝经超过12个月的女性。测量身高、体重、腰围、血压以及甘油三酯(TG)水平、总胆固醇(TC)水平、高密度脂蛋白胆固醇(HDL-C)水平和低密度脂蛋白胆固醇(LDL-C)的血浆水平。根据成人腰围标准(≥85 cm)诊断腹部肥胖。参照《中国成人血脂异常防治指南(2007年版)》中TG、TC、HDL-C和LDL-C的标准诊断血脂异常。采用Logistic回归分析腹部肥胖与血脂异常之间的关系。
腹部肥胖和血脂异常的发生率分别为13.6%(44/323)和29.7%(96/323)。腹部肥胖组血脂异常率显著高于对照组(43.2% 对27.6%,P = 0.036)。腰围与TG(r = 0.28,P < 0.01)和LDL-C(r = 0.20,P < 0.01)呈正相关,与HDL-C(r = -0.26,P < 0.01)呈负相关。多因素Logistic回归分析显示,腹部肥胖使血脂异常风险显著增加(OR = 2.07,95%CI 1.04 - 4.13,P = 0.039)。TG和HDL-C的OR分别为3.81(95%CI 1.69 - 8.60,P = 0.001)和3.19(95%CI 1.36 - 7.52,P = 0.008)。
腹部肥胖可能是绝经后女性血脂异常的一个危险因素。