大肠杆菌K-12中由转座子Tn10介导的对各种四环素的抗性
Resistance to various tetracyclines mediated by transposon Tn10 in Escherichia coli K-12.
作者信息
Traub B, Beck C F
出版信息
Antimicrob Agents Chemother. 1985 May;27(5):879-81. doi: 10.1128/AAC.27.5.879.
Abstract
Levels of resistance to tetracycline, chlortetracycline, demethylchlortetracycline, doxycycline, oxytetracycline, methacycline, pyrrolidinotetracycline, minocycline, and beta-chelocardin of Escherichia coli K-12 carrying transposon Tn10 or defined DNA segments of Tn10 were determined. In all cases, tetA was the only gene required for resistance. Doxycycline was the most effective inducer of tetA gene expression.
摘要
测定了携带转座子Tn10或Tn10特定DNA片段的大肠杆菌K-12对四环素、金霉素、去甲基金霉素、强力霉素、土霉素、甲烯土霉素、吡咯烷四环素、米诺环素和β-氯卡定的抗性水平。在所有情况下，tetA是产生抗性所需的唯一基因。强力霉素是tetA基因表达最有效的诱导剂。
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2
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