Aoyagi T, Wada T, Kojima F, Nagai M, Akanuma Y, Akanuma H, Umezawa H
Biochem Int. 1985 May;10(5):821-7.
Plasma levels of various hydrolytic enzymes in diabetic patients, as diagnosed by their blood glucose levels, were compared with those of control subjects. Most of the levels of the aminopeptidase activities examined were significantly increased, while those of angiotensin-converting enzyme (ACE) and esterase decreased, in diabetic patients. The results of multivariate analysis suggest that the increased aminopeptidase activities are related rather to secondary organ lesions than to the primary pancreatic lesion. It seems that the blood glucose level is not necessarily a good indicator of metabolic abnormalities underlying this pathological condition.
通过血糖水平诊断的糖尿病患者血浆中各种水解酶的水平与对照受试者的水平进行了比较。在糖尿病患者中，所检测的大多数氨肽酶活性水平显著升高，而血管紧张素转换酶（ACE）和酯酶的水平则降低。多变量分析结果表明，氨肽酶活性增加与继发性器官病变而非原发性胰腺病变有关。血糖水平似乎不一定是这种病理状况潜在代谢异常的良好指标。
