Peng Ling-fang, Lu Li-he, Yang Li-guo, Lu Xue-ping, Cui Tao, Zhu Zhao-yun
Yao Xue Xue Bao. 2016 Aug;51(8):1281-4.
This study was conducted to investigate the chemical constituents in the root of Dysosma versipellis(Hance) M. Cheng. The constituents were isolated by silica gel, lichroprep RP-C(18) and pharmadex LH-20 column chromatography and the IR, MS, NMR, 2D-NMR spectroscopic analysis were employed for the structural elucidation. Ten compounds were isolated from the 95% ethanol extract of Dysosma versipellis, their structures were elucidated as dysoverine D (1), dysoverine F (2), dysoverine A (3), podoverine A (4), α-peltatin (5), rutin (6), kaempferol-3-O-β-D-glucopyranoside (7), quercetin-3-O-β-D-glucopyranoside (8), kaempferol (9) and quercetin (10). Compound 2 is a new compound, and compounds 1 and 3-6 were isolated from this plant for the first time.
本研究旨在探讨八角莲（Dysosma versipellis(Hance) M. Cheng）根中的化学成分。通过硅胶柱色谱、Lichroprep RP-C(18)柱色谱和Pharmadex LH-20柱色谱分离得到这些成分，并采用红外光谱（IR）、质谱（MS）、核磁共振（NMR）、二维核磁共振（2D-NMR）光谱分析对其结构进行解析。从八角莲95%乙醇提取物中分离得到10个化合物，其结构分别鉴定为八角莲碱D（1）、八角莲碱F（2）、八角莲碱A（3）、足叶草碱A（4）、α-盾叶鬼臼素（5）、芦丁（6）、山柰酚-3-O-β-D-葡萄糖苷（7）、槲皮素-3-O-β-D-葡萄糖苷（8）、山柰酚（9）和槲皮素（10）。化合物2为新化合物，化合物1和3 - 6为首次从该植物中分离得到。
