Shorin Iu P, Seliatitskaia V G, Kolosova N G, Kulikov V Iu
Biull Eksp Biol Med. 1985 Jun;99(6):669-71.
Adrenocortical function and the intensity of lipid peroxidation in the liver of animals fed the diet containing alpha-tocopherol (4 mg/day/rat for 7 days) and exposed to cold stress for 2, 5 and 20 hours were studied in vitro. It was established that alpha-tocopherol reduces the duration of the corticosterone secretion augmentation under cold stress but raises the sensitivity of the adrenals to ACTH. The action of the antioxidant correlated with its content in the tissues and inhibition of the cold-induced activation of lipid peroxidation.
在体外研究了给动物喂食含α-生育酚（4毫克/天/大鼠，持续7天）的日粮并使其暴露于冷应激2小时、5小时和20小时后，其肾上腺皮质功能及肝脏中脂质过氧化强度。结果表明，α-生育酚可缩短冷应激下皮质酮分泌增加的持续时间，但会提高肾上腺对促肾上腺皮质激素（ACTH）的敏感性。这种抗氧化剂的作用与其在组织中的含量相关，并能抑制冷诱导的脂质过氧化激活。
