Panasiuk E N, Skakun L N
Kosm Biol Aviakosm Med. 1985 Jan-Feb;19(1):48-52.
Experiments on white rats showed that exposure to hypokinesia increased peroxidation of unsaturated fatty acids of lipids of cell membranes, decreased the content of sulfhydryl groups, and increased the content of disulphide groups. This was very marked during the first 4-7 days, i.e., during the time of a distinct stress-reaction. At later stages the rate of free radical processes decreased slightly. In the recovery period that followed 7-day hypokinesia lipid peroxidation in the rats gradually returned to normal. The initiation of free radical reactions during hypokinesia can be prevented by means of antioxidants (acetate tocopherol, sodium selenite) and syrepar.
对白鼠的实验表明，暴露于运动不足环境会增加细胞膜脂质中不饱和脂肪酸的过氧化作用，降低巯基含量，并增加二硫键含量。在最初的4 - 7天，即在明显的应激反应期间，这种情况非常明显。在后期，自由基过程的速率略有下降。在7天运动不足后的恢复期，大鼠体内的脂质过氧化作用逐渐恢复正常。运动不足期间自由基反应的引发可以通过抗氧化剂（生育酚乙酸酯、亚硒酸钠）和syrepar来预防。
