Keyal Uma, Liu Yeqiang, Bhatta Anil Kumar
Department of Dermatopathology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.
Discov Med. 2018 May;25(139):225-233.
Inflammatory bowel disease (IBD) is a chronic relapsing disease of the gastrointestinal tract with unknown etiology and pathogenesis. It includes Crohn's disease (CD) and ulcerative colitis (UC). Approximately one-third of the patients with IBD are seen to develop extraintestinal manifestations, among which cutaneous manifestations are the most common and should be managed in close collaboration with a dermatologist. Depending upon the nature of the association, skin conditions associated with IBD can be listed under 4 categories: specific, reactive, secondary to malnutrition or malabsorption, and secondary to drug therapy. Skin conditions that do not fit into these categories are listed under the fifth category named as miscellaneous by some authors. The aim of the present review is to discuss some of the noteworthy skin disorders associated with IBD and highlight their importance in context to IBD.
炎症性肠病(IBD)是一种病因和发病机制不明的胃肠道慢性复发性疾病。它包括克罗恩病(CD)和溃疡性结肠炎(UC)。约三分之一的IBD患者会出现肠外表现,其中皮肤表现最为常见,应与皮肤科医生密切合作进行处理。根据关联的性质,与IBD相关的皮肤状况可分为4类:特异性、反应性、继发于营养不良或吸收不良以及继发于药物治疗。不符合这些类别的皮肤状况被列为第五类,一些作者称之为杂项。本综述的目的是讨论一些与IBD相关的值得注意的皮肤疾病,并强调它们在IBD背景下的重要性。