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成人头颈部软组织肉瘤

Soft tissue sarcomas of the adult head and neck.

作者信息

Greager J A, Patel M K, Briele H A, Walker M J, Das Gupta T K

出版信息

Cancer. 1985 Aug 15;56(4):820-4. doi: 10.1002/1097-0142(19850815)56:4<820::aid-cncr2820560420>3.0.co;2-p.

Abstract

From 1969 to 1983, 53 adult patients with head and neck soft tissue sarcomas were evaluated and treated by the Division of Surgical Oncology at the University of Illinois. The most common anatomic location was the neck (36%), and these patients had the highest 5-year disease-free survival rate (67%). Fibrosarcoma was the most common histologic type (26%); patients with aggressive fibromatosis had the longest mean survival time (93 months). The mean overall survival time was 58.7 months, and the disease-free 2-year, 5-year, and 10-year survival rates were 68%, 54%, and 28%, respectively. Wide excision was the treatment of choice, with adjuvant radiotherapy or chemotherapy, or both, used in selected patients. In all of the long-term survivors, the tumors were either well-differentiated or less than or equal to 5.0 cm in diameter. It is apparent that aggressive therapy of such tumors can provide good long-term results.

摘要

1969年至1983年期间,伊利诺伊大学外科肿瘤学部门对53例成年头颈部软组织肉瘤患者进行了评估和治疗。最常见的解剖部位是颈部(36%),这些患者的5年无病生存率最高(67%)。纤维肉瘤是最常见的组织学类型(26%);侵袭性纤维瘤病患者的平均生存时间最长(93个月)。总体平均生存时间为58.7个月,2年、5年和10年无病生存率分别为68%、54%和28%。广泛切除是首选治疗方法,部分患者采用辅助放疗或化疗,或两者兼用。在所有长期存活者中,肿瘤要么分化良好,要么直径小于或等于5.0厘米。显然,对此类肿瘤进行积极治疗可取得良好的长期效果。

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