George T K, di Sant'agnese P A, Bennett J M
Cancer. 1985 Sep 1;56(5):1034-8. doi: 10.1002/1097-0142(19850901)56:5<1034::aid-cncr2820560511>3.0.co;2-l.
Merkel cell carcinomas (also known as trabecular carcinomas) are primary cutaneous small cell neuroendocrine neoplasms with the potential to metastasize. Control of disseminated disease is therefore important. A case of metastatic Merkel cell carcinoma with an excellent response to chemotherapy is presented. The regimen chosen for this case is similar to that used for bronchogenic small cell anaplastic carcinoma. The reason for selecting this regimen was the common neuroendocrine differentiation and the similar histopathologic features of these two tumors. Only a few reports have described chemotherapy for Merkel cell carcinoma and similar agents were used. These cases are reviewed and critically analyzed.
默克尔细胞癌（也称为小梁癌）是原发性皮肤小细胞神经内分泌肿瘤，具有转移潜能。因此，控制播散性疾病很重要。本文介绍了一例转移性默克尔细胞癌对化疗有良好反应的病例。该病例选择的治疗方案与用于支气管源性小细胞间变性癌的方案相似。选择该方案的原因是这两种肿瘤具有共同的神经内分泌分化和相似的组织病理学特征。仅有少数报告描述了默克尔细胞癌的化疗情况，且使用的是类似药物。对这些病例进行了回顾和批判性分析。
