Gold J W
Cancer Res. 1985 Sep;45(9 Suppl):4652s-4654s.
Infectious complications are the cause of death in the overwhelming majority of patients with the acquired immunodeficiency syndrome (AIDS). These infectious complications are outstanding in severity and number. Infecting organisms are mainly those which take advantage of defective T-cell function. Many cause latent infections which can reactivate and cause disease in AIDS patients because of immunosuppression. Serological diagnosis of infections in AIDS patients is complicated because of the defect in B-cell function; rising antibody titers are not observed in most patients with infectious complications. The natural history of AIDS is one of repeated infections leading to a fatal outcome. However, treatment for most of the bacterial, fungal, and parasitic infections is effective. Treatment of some of these infections must be prolonged indefinitely because of the tendency to relapse.
感染性并发症是绝大多数获得性免疫缺陷综合征（艾滋病）患者的死因。这些感染性并发症在严重程度和数量上都很突出。感染源主要是那些利用T细胞功能缺陷的病原体。许多病原体引发潜伏感染，由于免疫抑制，这些潜伏感染在艾滋病患者体内可能重新激活并引发疾病。艾滋病患者感染的血清学诊断很复杂，因为B细胞功能存在缺陷；大多数有感染性并发症的患者并未观察到抗体滴度升高。艾滋病的自然病程是反复感染导致致命结局。然而，大多数细菌、真菌和寄生虫感染的治疗是有效的。由于存在复发倾向，其中一些感染的治疗必须无限期延长。
