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无症状个体的颈椎前凸：一项荟萃分析。

Cervical lordosis in asymptomatic individuals: a meta-analysis.

作者信息

Guo Guang-Ming, Li Jun, Diao Qing-Xun, Zhu Tai-Hang, Song Zhong-Xue, Guo Yang-Yang, Gao Yan-Zheng

机构信息

Department of Orthopaedics, Henan Zhoukou Union Orthopaedic Hospital, East Section, Taihao Road, Zhoukou, 466000, Henan, China.

Department of Orthopaedics, Henan Province People's Hospital, Zhengzhou, 450000, Henan, China.

出版信息

J Orthop Surg Res. 2018 Jun 15;13(1):147. doi: 10.1186/s13018-018-0854-6.

DOI:10.1186/s13018-018-0854-6
PMID:29907118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6003173/
Abstract

BACKGROUND

Cervical lordosis has important clinical and surgical implications. Cervical spine curvature is reported with considerable variability in individual studies. The aim of this study was to examine the existence and extent of cervical lordosis in asymptomatic individuals and to evaluate its relationship with age and gender.

METHODS

A comprehensive literature search was conducted in several electronic databases. Study selection was based on pre-determined eligibility criteria. Random effects meta-analyses were performed to estimate the proportion of asymptomatic individuals with lordosis and the effect size of cervical lordotic curvature in these individuals which followed metaregression analysis to examine the factors affecting cervical lordosis. Data from 21 studies (15,364 asymptomatic individuals, age 42.30 years [95% confidence interval 36.42, 48.18], 54.2% males) were used in the present study.

RESULTS

In this population, 63.99% [95% confidence interval 44.94, 83.03] individuals possessed lordotic curvature. Degree of lordotic curvature differed by method of measurement; 12.71° [6.59, 18.84] with Cobb C2-C7 method and 18.55° [14.48, 22.63] with posterior tangent method. Lordotic curvature was not significantly different between symptomatic and asymptomatic individuals but was significantly higher in males in comparison with females. Age was not significantly associated with lordotic cervical curvature.

CONCLUSION

Majority of the asymptomatic individuals possesses lordotic cervical curvature which is higher in males than in females but have no relationship with age or symptoms.

摘要

背景

颈椎前凸具有重要的临床和手术意义。在个体研究中，颈椎曲度的报道存在很大差异。本研究的目的是检查无症状个体中颈椎前凸的存在情况和程度，并评估其与年龄和性别的关系。

方法

在多个电子数据库中进行了全面的文献检索。研究选择基于预先确定的纳入标准。进行随机效应荟萃分析，以估计有前凸的无症状个体的比例以及这些个体颈椎前凸曲度的效应大小，随后进行元回归分析以检查影响颈椎前凸的因素。本研究使用了来自21项研究的数据（15364名无症状个体，年龄42.30岁[95%置信区间36.42, 48.18]，男性占54.2%）。

结果

在该人群中，63.99%[95%置信区间44.94, 83.03]的个体存在前凸曲度。前凸曲度的程度因测量方法而异；采用Cobb C2-C7法为12.71°[6.59, 18.84]，采用后切线法为18.55°[14.48, 22.63]。有症状和无症状个体之间的前凸曲度无显著差异，但男性的前凸曲度显著高于女性。年龄与颈椎前凸曲度无显著相关性。

结论

大多数无症状个体存在颈椎前凸曲度，男性高于女性，但与年龄或症状无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/98cf7317616d/13018_2018_854_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/055653848097/13018_2018_854_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/5bcc90e99010/13018_2018_854_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/3f0fb7929e7a/13018_2018_854_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/1d321703957d/13018_2018_854_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/947833523c9a/13018_2018_854_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/98cf7317616d/13018_2018_854_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/055653848097/13018_2018_854_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/5bcc90e99010/13018_2018_854_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/3f0fb7929e7a/13018_2018_854_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/1d321703957d/13018_2018_854_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/947833523c9a/13018_2018_854_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0878/6003173/98cf7317616d/13018_2018_854_Fig6_HTML.jpg

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