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Use of ribavirin in viruses other than hepatitis C. A review of the evidence.利巴韦林在丙型肝炎以外病毒中的应用。证据综述。
Enferm Infecc Microbiol Clin (Engl Ed). 2019 Nov;37(9):602-608. doi: 10.1016/j.eimc.2018.05.008. Epub 2018 Jun 12.
2
[Use of ribavirin in viruses other than hepatitis C. A review of the evidence].[利巴韦林在丙型肝炎以外病毒中的应用。证据综述]
Enferm Infecc Microbiol Clin. 2019 Nov;37(9):602-608. doi: 10.1016/j.eimc.2018.05.008. Epub 2018 Jun 12.
3
Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses.低剂量利巴韦林可增强法匹拉韦对出血热病毒的抗病毒活性。
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The efficacy of oral ribavirin in the treatment of crimean-congo hemorrhagic fever in Iran.口服利巴韦林治疗伊朗克里米亚-刚果出血热的疗效
Clin Infect Dis. 2003 Jun 15;36(12):1613-8. doi: 10.1086/375058. Epub 2003 Jun 4.
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Evaluation of antiviral efficacy of ribavirin, arbidol, and T-705 (favipiravir) in a mouse model for Crimean-Congo hemorrhagic fever.在克里米亚-刚果出血热小鼠模型中对利巴韦林、阿比多尔和T-705（法匹拉韦）抗病毒疗效的评估。
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本文引用的文献

1
The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2015.2015年韩国首例导致中东呼吸综合征冠状病毒（MERS-CoV）疫情爆发的输入性病例的临床及病毒学特征
BMC Infect Dis. 2017 Jul 14;17(1):498. doi: 10.1186/s12879-017-2576-5.
2
Insufficient efficacy and safety of intravenous ribavirin in treatment of haemorrhagic fever with renal syndrome caused by Puumala virus.静脉用利巴韦林治疗普马拉病毒引起的肾综合征出血热疗效和安全性不足。
Infect Dis (Lond). 2017 Jul;49(7):514-520. doi: 10.1080/23744235.2017.1293841. Epub 2017 Mar 3.
3
Severe community-acquired adenovirus pneumonia treated with oral ribavirin: a case report.口服利巴韦林治疗重症社区获得性腺病毒肺炎：一例报告
BMC Res Notes. 2017 Jan 18;10(1):47. doi: 10.1186/s13104-016-2370-2.
4
Postexposure prophylaxis for Lassa fever: Experience from a recent outbreak in Nigeria.拉沙热暴露后预防：来自尼日利亚近期一次疫情的经验。
Niger Med J. 2016 Jul-Aug;57(4):246-50. doi: 10.4103/0300-1652.188362.
5
[The therapeutic effect of high flow nasal cannula oxygen therapy for the first imported case of Middle East respiratory syndrome to China].[高流量鼻导管吸氧疗法对中国首例输入性中东呼吸综合征病例的治疗效果]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Oct;27(10):841-4.
6
Severe Community-Acquired Pneumonia Caused by Human Adenovirus in Immunocompetent Adults: A Multicenter Case Series.免疫功能正常成人社区获得性重症肺炎：多中心病例系列。
PLoS One. 2016 Mar 11;11(3):e0151199. doi: 10.1371/journal.pone.0151199. eCollection 2016.
7
Middle East Respiratory Syndrome Coronavirus during Pregnancy, Abu Dhabi, United Arab Emirates, 2013.2013年，阿拉伯联合酋长国阿布扎比，孕期感染中东呼吸综合征冠状病毒情况
Emerg Infect Dis. 2016 Mar;22(3):515-7. doi: 10.3201/eid2203.151049.
8
Acute Management and Long-Term Survival Among Subjects With Severe Middle East Respiratory Syndrome Coronavirus Pneumonia and ARDS.中东呼吸综合征冠状病毒重症肺炎及急性呼吸窘迫综合征患者的急性处理与长期生存情况
Respir Care. 2016 Mar;61(3):340-8. doi: 10.4187/respcare.04325. Epub 2015 Dec 23.
9
Combination therapy with lopinavir/ritonavir, ribavirin and interferon-α for Middle East respiratory syndrome.洛匹那韦/利托那韦、利巴韦林和α干扰素联合治疗中东呼吸综合征
Antivir Ther. 2016;21(5):455-9. doi: 10.3851/IMP3002. Epub 2015 Oct 22.
10
IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study.干扰素-α2a或干扰素-β1a联合利巴韦林治疗中东呼吸综合征冠状病毒肺炎：一项回顾性研究。
J Antimicrob Chemother. 2015 Jul;70(7):2129-32. doi: 10.1093/jac/dkv085. Epub 2015 Apr 21.

利巴韦林在丙型肝炎以外病毒中的应用。证据综述。

Use of ribavirin in viruses other than hepatitis C. A review of the evidence.

作者信息

Ramírez-Olivencia German, Estébanez Miriam, Membrillo Francisco Javier, Ybarra Maria Del Carmen

机构信息

Unidad de Aislamiento de Alto Nivel, Hospital Central de la Defensa Gómez Ulla, Madrid, España.

Unidad de Aislamiento de Alto Nivel, Hospital Central de la Defensa Gómez Ulla, Madrid, España.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2019 Nov;37(9):602-608. doi: 10.1016/j.eimc.2018.05.008. Epub 2018 Jun 12.

DOI:10.1016/j.eimc.2018.05.008
PMID:29907366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7195261/
Abstract

Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitisC virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus.

摘要

利巴韦林是一种对多种病毒具有抗病毒活性的分子。在临床实践中，它几乎专门用于治疗丙型肝炎病毒。然而，在其他一些疾病中它可能也有益处，并且它具有适合口服、静脉注射和吸入给药的优点。我们对主要药物机构（西班牙、欧洲和美国）的适应证以及其他可能的适应证进行了综述，主要包括出血热和冠状病毒感染。