Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA.
Learn Mem. 2013 Oct 15;20(11):607-10. doi: 10.1101/lm.032490.113.
We tested proposals that medial temporal lobe (MTL) structures support not just memory but certain kinds of visual perception as well. Patients with hippocampal lesions or larger MTL lesions attempted to identify the unique object among twin pairs of objects that had a high degree of feature overlap. Patients were markedly impaired under the more difficult task conditions. However, the deficit was fully rescued when patients used a pencil to draw lines between the twin pairs, thereby eliminating the need to hold material in memory as they worked at each display. The perceptual demands of the task were presumably the same with or without this memory aid. Accordingly, the results suggest that the deficit on this and similar tasks, which involve comparisons across stimuli, are better understood in terms of impaired memory rather than impaired perception.
我们测试了内侧颞叶（MTL）结构不仅支持记忆，还支持某些特定类型的视觉感知的假设。患有海马体损伤或更大的 MTL 损伤的患者试图在具有高度特征重叠的一对双胞胎物体中识别出独特的物体。当患者在更困难的任务条件下时，他们的表现明显受损。然而，当患者使用铅笔在双胞胎之间画线时，缺陷就完全得到了弥补，从而消除了在处理每个显示器时在记忆中保留材料的需要。这项任务的感知需求无论是否有这种记忆辅助，都应该是相同的。因此，这些结果表明，在涉及刺激间比较的此类和类似任务上的缺陷，最好从受损的记忆而不是受损的感知的角度来理解。
