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评估博来霉素皮损内注射治疗跖疣的疗效:临床和皮肤镜评估。

Evaluation of intralesional injection of bleomycin in the treatment of plantar warts: clinical and dermoscopic evaluation.

机构信息

Department of Dermatology, Faculty of Medicine, Minia University, Al-Minya, Egypt.

Minia Dermatology Hospital, Ministry of Health, Al-Minya, Egypt.

出版信息

Int J Dermatol. 2018 Dec;57(12):1533-1537. doi: 10.1111/ijd.14092. Epub 2018 Jun 15.

Abstract

BACKGROUND

Treatment of plantar warts is difficult and requires multiple treatments, and they are more refractory to treatment than common warts. Intralesional bleomycin has been used in the treatment of warts with varying degrees of success.

AIM

The aim of the present work is to evaluate the efficacy of intralesional injection of bleomycin in the treatment of plantar warts based on clinical and dermoscopic observations.

PATIENTS AND METHODS

Bleomycin (1 mg/ml) was injected intralesionally into the pared plantar wart every 2 weeks for a maximum of four sessions. Patients were followed both clinically and by the use of dermoscope.

RESULTS

The cure rate of plantar warts treated with bleomycin was 69.3% with minimal and tolerable side effects.

CONCLUSION

Intralesional injection of bleomycin is an effective and safe treatment of plantar warts. Dermoscope is recommended in the evaluation of treatment success, as it can accurately tell if the wart needs further treatment, preventing premature stoppage of the treatment, thus decreasing the possibility of recurrences.

摘要

背景

足底疣的治疗较为困难,需要多次治疗,且比普通疣更难治疗。瘤内平阳霉素已被用于治疗疣,取得了不同程度的成功。

目的

本研究旨在通过临床和皮肤镜观察评估瘤内注射平阳霉素治疗足底疣的疗效。

患者和方法

将平阳霉素(1mg/ml)瘤内注射到修剪过的足底疣中,每 2 周注射一次,最多 4 次。通过临床和皮肤镜对患者进行随访。

结果

用平阳霉素治疗的足底疣的治愈率为 69.3%,副作用最小且可耐受。

结论

瘤内注射平阳霉素是治疗足底疣的一种有效且安全的方法。皮肤镜推荐用于评估治疗效果,因为它可以准确判断疣是否需要进一步治疗,防止过早停止治疗,从而降低复发的可能性。

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