豆象 Bruchidius dorsalis 在皂荚种子内建造的蛹壳中的硫酸化嘌呤生物碱糖苷

Sulfated Purine Alkaloid Glycosides from the Pupal Case Built by the Bruchid Beetle Bruchidius dorsalis Inside the Seed of Gleditsia japonica.

作者信息

Harauchi Yui, Muranaka Kyo, Ohta Emi, Kawachi Hiroyuki, Imamura-Jinda Aya, Nehira Tatsuo, Ômura Hisashi, Ohta Shinji

机构信息

Graduate School of Biosphere Science, Hiroshima University, 1-7-1 Kagamiyama, Higashi-Hiroshima, 739-8521, Japan.

Graduate School of Bioscience, Nagahama Institute for Bioscience and Technology, 1266 Tamura-cho, Nagahama-shi, Shiga, 526-0829, Japan.

出版信息

Chem Biodivers. 2018 Aug;15(8):e1800154. doi: 10.1002/cbdv.201800154. Epub 2018 Jul 3.

DOI:10.1002/cbdv.201800154

PMID:29907997

Abstract

Three new sulfated isoguanine alkaloid glycosides, designated as saikachinoside A monosulfate (1), saikachinoside A disulfate (2), and locustoside B disulfate (3), have been isolated from the pupal case of the wild bruchid seed beetle Bruchidius dorsalis (Chrysomelidae, Bruchinae) infesting the seed of Gleditsia japonica Miq. (Fabaceae). Their structures were determined by spectroscopic methods and the inhibitory activity of 2 and 3 against acid phosphatase was evaluated.

摘要

从寄生于皂荚（豆科）种子上的野生豆象 Bruchidius dorsalis（叶甲科，豆象亚科）的蛹壳中分离出三种新的硫酸化异鸟嘌呤生物碱苷，分别命名为单硫酸化槐刺糖苷 A（1）、二硫酸化槐刺糖苷 A（2）和二硫酸化刺槐糖苷 B（3）。通过光谱方法确定了它们的结构，并评估了 2 和 3 对酸性磷酸酶的抑制活性。