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在年轻健康受试者中,比较食用蜂蜜与蔗糖对血脂水平的影响(随机临床试验)。

The effect of honey consumption compared with sucrose on lipid profile in young healthy subjects (randomized clinical trial).

作者信息

Rasad Hamid, Entezari Mohammad Hassan, Ghadiri Ehsan, Mahaki Behzad, Pahlavani Naseh

机构信息

Health Center of Makoo, Urmia University of Medical Sciences, Urmia, Iran.

Food Security Research Center and Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Clin Nutr ESPEN. 2018 Aug;26:8-12. doi: 10.1016/j.clnesp.2018.04.016. Epub 2018 May 19.

DOI:10.1016/j.clnesp.2018.04.016
PMID:29908688
Abstract

BACKGROUND AND AIMS

Several studies have demonstrated that honey consumption has beneficial effects on cardiovascular disease indicators. The current study aimed to investigate the effect of honey consumption compared with sucrose on lipid profile among young healthy subjects.

METHODS

Sixty healthy subjects, aged 18-30 years, were randomly recruited into this double blind randomized trial and assigned into two groups: honey (received 70 g honey per day) and sucrose (received 70 g sucrose per day) groups. Total cholesterol, TG, LDL and HDL were measured in the control and intervention groups at the beginning and end of study.

RESULTS

In this trial, the baseline FBS, SBP and DBP were not different between honey and sucrose groups (P > 0.3). We found evidence indicating consumption of honey can decrease total cholesterol, TG and LDL and increase HDL in healthy young subjects, but intake of sucrose increase total cholesterol, TG and LDL and decreased HDL. In all of these analyses, confounding variable including age, physical activity and some nutrient intake were adjusted.

CONCLUSIONS

Honey consumption can improve the lipid profile such as; total cholesterol, TG and LDL and increase HDL, but consumption of sucrose increases total cholesterol, TG and LDL and decreases HDL. Further clinical trial studies are required to confirm our findings.

摘要

背景与目的

多项研究表明,食用蜂蜜对心血管疾病指标有有益影响。本研究旨在调查在年轻健康受试者中,与蔗糖相比,食用蜂蜜对血脂的影响。

方法

60名年龄在18至30岁的健康受试者被随机纳入这项双盲随机试验,并分为两组:蜂蜜组(每天摄入70克蜂蜜)和蔗糖组(每天摄入70克蔗糖)。在研究开始和结束时,对对照组和干预组的总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白进行了测量。

结果

在本试验中,蜂蜜组和蔗糖组的基线空腹血糖、收缩压和舒张压无差异(P>0.3)。我们发现有证据表明,食用蜂蜜可降低健康年轻受试者的总胆固醇、甘油三酯和低密度脂蛋白,并提高高密度脂蛋白,但摄入蔗糖会增加总胆固醇、甘油三酯和低密度脂蛋白,并降低高密度脂蛋白。在所有这些分析中,对包括年龄、身体活动和一些营养素摄入在内的混杂变量进行了调整。

结论

食用蜂蜜可改善血脂状况,如降低总胆固醇、甘油三酯和低密度脂蛋白,并提高高密度脂蛋白,但食用蔗糖会增加总胆固醇、甘油三酯和低密度脂蛋白,并降低高密度脂蛋白。需要进一步的临床试验研究来证实我们的发现。

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