Amar Jacques
CHU de Toulouse, ESH excellence center, fédération de cardiologie, service d'hypertension artérielle, 1, avenue du Professeur-Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France.
Presse Med. 2018 Sep;47(9):775-779. doi: 10.1016/j.lpm.2018.03.016. Epub 2018 Jun 13.
When analyzing the microbiota-host crosstalk, we have to consider three participants in this dialogue: the gut microbiota, the intestinal barrier and bacterial translocation. Experimental data demonstrate that host microbiota crosstalk plays a causal on the regulation of blood pressure, glucose metabolism and the development of atherosclerosis. Host microbiota crosstalk is associated in humans with main cardiovascular risk factors notably hypertension and type 2 diabetes. Host microbiota crosstalk is associated in humans with the onset of cardiovascular diseases. The Mediterranean diet has proven as proven to be an effective strategy in improving cardiovascular prognosis and in changing gut microbiota.
在分析微生物群与宿主的相互作用时，我们必须考虑这种对话中的三个参与者：肠道微生物群、肠道屏障和细菌易位。实验数据表明，宿主微生物群的相互作用在血压调节、葡萄糖代谢和动脉粥样硬化的发展中起因果作用。在人类中，宿主微生物群的相互作用与主要心血管危险因素显著相关，尤其是高血压和2型糖尿病。在人类中，宿主微生物群的相互作用与心血管疾病的发生有关。地中海饮食已被证明是改善心血管预后和改变肠道微生物群的有效策略。
