Guy Joshua H, Vincent Grace E
School of Health, Medical and Applied Sciences, Central Queensland University, Cairns 4870, Australia.
School of Health, Medical and Applied Sciences, Central Queensland University, Adelaide 5034, Australia.
Sports (Basel). 2018 Feb 6;6(1):12. doi: 10.3390/sports6010012.
Exercise-induced heat production is further elevated by exercise performed in hot conditions and this can subsequently impact inflammation, and gastrointestinal (GI) health. Implementing nutrition and supplementation strategies under these conditions may support the hyperthermic response, the systemic inflammatory response, GI permeability and integrity, and exercise performance. Therefore, the aim of this brief review is to explore athletes' inflammatory response of two key biomarkers, lipopolysaccharide (LPS), and interleukin-6 (IL-6), and provide nutrition and supplementation recommendations when exercising in hot conditions. There is emerging evidence that probiotics, glutamine, and vitamin C can preserve GI integrity, which may improve performance during exercise in the heat. Glucose rich food when consumed with water, before and during exercise in the heat, also appear to limit endotoxemia, preserve GI integrity, and reduce the incidence of GI disturbances compared with water alone. The use of non-steroidal anti-inflammatory drugs (NSAIDs) may compromise GI integrity and this may result in greater leakage of endotoxins during long duration exercise in the heat. Further work is required to elucidate the impact of nutrition and supplementation strategies, in particular the use of NSAIDs, when exercising in the heat.
在炎热环境下进行运动时，运动诱导的产热会进一步升高，这随后可能会影响炎症以及胃肠道（GI）健康。在这些条件下实施营养和补充策略可能有助于热调节反应、全身炎症反应、胃肠道通透性和完整性以及运动表现。因此，本简要综述的目的是探讨运动员对两种关键生物标志物——脂多糖（LPS）和白细胞介素-6（IL-6）的炎症反应，并提供在炎热环境下运动时的营养和补充建议。有新证据表明，益生菌、谷氨酰胺和维生素C可以维持胃肠道完整性，这可能会改善在炎热环境下运动时的表现。在炎热环境下运动前和运动期间，富含葡萄糖的食物与水一起食用时，与单独饮水相比，似乎也能限制内毒素血症、维持胃肠道完整性并降低胃肠道紊乱的发生率。使用非甾体抗炎药（NSAIDs）可能会损害胃肠道完整性，这可能会导致在炎热环境下长时间运动期间内毒素泄漏增加。需要进一步的研究来阐明在炎热环境下运动时营养和补充策略的影响，特别是NSAIDs的使用。
