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我们是否通过强化治疗来弥补糖尿病患者身体活动的不足?

Are We Compensating for the Lack of Physical Activity in Our Diabetic Patients with Treatment Intensification?

作者信息

Maja Cigrovski Berkovic Maja Cigrovski, Bilic-Curcic Ines, Gradiser Marina, Herman-Mahecic Davorka, Cigrovski Vjekoslav, Ivandic Marul

机构信息

Clinical Department of Endocrinology, Diabetes and Metabolism, University Hospital Centre "Sestre Milosrdnice", 10000 Zagreb, Croatia.

Faculty of Medicine, J. J. Strossmayer University Osijek, Clinical Hospital Center Osijek, 31000 Osijek, Croatia.

出版信息

Sports (Basel). 2017 Aug 7;5(3):58. doi: 10.3390/sports5030058.

DOI:10.3390/sports5030058
PMID:29910418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5968955/
Abstract

BACKGROUND

We studied the association between leisure time physical activity (LTPA) and glycemic control, body mass index (BMI), and hypoglycemic incidents in type 1 (T1DM) and type 2 diabetes patients (T2DM).

METHODS

This is a cross-sectional study of 198 diabetic patients (60 with type 1 diabetes, 138 with type 2 diabetes). LTPA was assessed by a validated 12-month questionnaire. Patients were grouped as sedentary and moderately to vigorously active. Outcome measures were Hemoglobin A1c (HbA1c), BMI, and hypoglycemic episodes.

RESULTS

LTPA effect on the HbA1c reduction was present in diabetes type 1 patients. Patients who were involved in the moderate to vigorous-intensity physical activity had a greater decrease in the HbA1c (p = 0.048) than patients with low physical activity (p = 0.085). Level of LTPA was neither associated with increased number of hypoglycemic episodes, nor BMI. After an average of 4 years of diabetes, the number of patients requiring more than one antidiabetic agent increased, although the observed difference did not correlate with LTPA level.

CONCLUSIONS

LTPA has an influence on the regulation of diabetes type 1, and intensification of medical treatment is compensating for the lack of lifestyle change-especially in type 2 diabetics.

摘要

背景

我们研究了休闲时间身体活动(LTPA)与1型糖尿病(T1DM)和2型糖尿病患者(T2DM)的血糖控制、体重指数(BMI)及低血糖事件之间的关联。

方法

这是一项对198例糖尿病患者(60例1型糖尿病患者,138例2型糖尿病患者)的横断面研究。通过一份经验证的12个月调查问卷评估LTPA。患者被分为久坐不动组和中度至剧烈活动组。观察指标为糖化血红蛋白(HbA1c)、BMI和低血糖发作情况。

结果

LTPA对1型糖尿病患者的HbA1c降低有影响。参与中度至剧烈强度身体活动的患者HbA1c下降幅度(p = 0.048)大于身体活动量低的患者(p = 0.085)。LTPA水平与低血糖发作次数增加及BMI均无关联。糖尿病平均病程4年后,需要一种以上抗糖尿病药物治疗的患者数量增加,尽管观察到的差异与LTPA水平无关。

结论

LTPA对1型糖尿病的病情调控有影响,而强化药物治疗正在弥补生活方式改变不足的问题——尤其是在2型糖尿病患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d09/5968955/d841b4595124/sports-05-00058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d09/5968955/d841b4595124/sports-05-00058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d09/5968955/d841b4595124/sports-05-00058-g001.jpg

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Diabetologia. 2015 Aug;58(8):1730-4. doi: 10.1007/s00125-015-3617-5. Epub 2015 May 8.
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PLoS One. 2014 Jun 4;9(6):e98768. doi: 10.1371/journal.pone.0098768. eCollection 2014.
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Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000 people.2型糖尿病患者的临床惰性:一项对8万多人的回顾性队列研究。
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Leisure-time physical activity is a significant predictor of stroke and total mortality in Japanese patients with type 2 diabetes: analysis from the Japan Diabetes Complications Study (JDCS).日本 2 型糖尿病患者中,闲暇时体力活动是卒中及全因死亡的重要预测因子:来自日本糖尿病并发症研究(JDCS)的分析。
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