Ramatillah Diana Laila, Syed Sulaiman Syed Azhar, Khan Amer Hayat
Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, Penang, Malaysia.
J Glob Infect Dis. 2018 Apr-Jun;10(2):37-41. doi: 10.4103/jgid.jgid_85_17.
According to the Association of Nephrologist in Indonesia (Pernefri) recommendation, isolation and using special hemodialysis machines are not necessary for hemodialysis (HD) patients who have been infected by hepatitis C virus (HCV), while according to the Ministry of Health Malaysia recommendation, hepatitis C patients should be dialyzed in a separate room or a separate area with a fixed partition and dedicated machines.
The aim of this study was to identify the correlation between the recommendation which had been followed by two HD centers in different countries and the impact of that on the hepatitis C infection issue.
A cohort prospective and retrospective study was done in this research. The study included HD patients who were followed up for 9 months and who died in the last 5 years. Universal sampling was used to select the patients based on inclusion criteria.
There was a significant relationship between HCV during the first checkup and HCV during the second checkup during the 9-month follow-up of HD patients in a HD center, Jakarta, Indonesia. The total number of patients who had hepatitis C during the first and second checkups was also different in this HD center.
Besides providing special HD rooms and machines for HD patients with hepatitis C, minimizing blood transfusion to the patients on HD is also important to reduce the chance for the patients to acquire hepatitis C and to increase the percentage of survival.
根据印度尼西亚肾脏病学家协会(Pernefri)的建议,对于已感染丙型肝炎病毒(HCV)的血液透析(HD)患者,无需隔离并使用特殊的血液透析机,而根据马来西亚卫生部的建议,丙型肝炎患者应在单独的房间或有固定隔断和专用机器的单独区域进行透析。
本研究的目的是确定不同国家的两个血液透析中心所遵循的建议之间的相关性及其对丙型肝炎感染问题的影响。
本研究采用队列前瞻性和回顾性研究。该研究纳入了随访9个月且在过去5年中死亡的血液透析患者。根据纳入标准采用全样本抽样选择患者。
在印度尼西亚雅加达的一个血液透析中心,对血液透析患者进行9个月随访期间,首次检查时的HCV与第二次检查时的HCV之间存在显著关系。该血液透析中心首次和第二次检查时患有丙型肝炎的患者总数也有所不同。
除了为丙型肝炎血液透析患者提供特殊的透析室和机器外,尽量减少对血液透析患者的输血对于降低患者感染丙型肝炎的几率和提高生存率也很重要。