Kim Karen M, Shannon Francis, Paone Gaetano, Lall Shelly, Batra Sanjay, Boeve Theodore, DeLucia Alphonse, Patel Himanshu J, Theurer Patricia F, He Chang, Clark Melissa J, Sultan Ibrahim, Deeb George Michael, Prager Richard L
Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan.
J Card Surg. 2018 Aug;33(8):424-430. doi: 10.1111/jocs.13740. Epub 2018 Jun 17.
Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic valve replacement (SAVR) for the treatment of aortic stenosis in patients at intermediate, high, and extreme risk for mortality from SAVR. We examined recent trends in aortic valve replacement (AVR) in Michigan.
The Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative (MSTCVS-QC) database was used to determine the number of SAVR and TAVR cases performed from January 2012 through June 2017. Patients were divided into low, intermediate, high, and extreme risk groups based on STS predicted risk of mortality (PROM). TAVR patients in the MSTCVS-QC database were also matched with those in the Transcatheter Valve Therapy Registry to determine their Heart Team-designated risk category.
During the study period 9517 SAVR and 4470 TAVR cases were performed. Total annual AVR volume increased by 40.0% (from 2086 to 2920), with a 13.3% decrease in number of SAVR cases (from 1892 to 1640) and a 560% increase in number of TAVR cases (from 194 to 1280). Greater than 90% of SAVR patients had PROM ≤8%. While >70% of TAVR patients had PROM ≤ 8%, they were mostly designated as high or extreme risk by a Heart Team.
During the study period, SAVR volume gradually declined and TAVR volume dramatically increased. This was mostly due to a new group of patients with lower STS PROM who were designated as higher risk by a Heart Team due to characteristics not completely captured by the STS PROM score.
经导管主动脉瓣置换术(TAVR)是外科主动脉瓣置换术(SAVR)的一种替代方法,用于治疗手术主动脉瓣置换术死亡风险为中度、高度和极高的主动脉瓣狭窄患者。我们研究了密歇根州主动脉瓣置换术(AVR)的近期趋势。
使用密歇根胸心血管外科医生质量协作组织(MSTCVS-QC)数据库确定2012年1月至2017年6月期间进行的SAVR和TAVR病例数。根据胸外科医师协会(STS)预测的死亡风险(PROM)将患者分为低、中、高和极高风险组。MSTCVS-QC数据库中的TAVR患者也与经导管瓣膜治疗注册中心的患者进行匹配,以确定其心脏团队指定的风险类别。
在研究期间,共进行了9517例SAVR和4470例TAVR手术。每年AVR总量增加了40.0%(从2086例增至2920例),SAVR病例数减少了13.3%(从1892例减至1640例),TAVR病例数增加了560%(从194例增至1280例)。超过90%的SAVR患者PROM≤8%。虽然超过70%的TAVR患者PROM≤8%,但他们大多被心脏团队指定为高风险或极高风险。
在研究期间,SAVR数量逐渐下降,TAVR数量显著增加。这主要是由于一组新的患者,其STS PROM较低,但由于STS PROM评分未完全涵盖的特征,被心脏团队指定为较高风险。