Kubasiewicz-Ross Paweł, Hadzik Jakub, Dominiak Marzena
Department of Oral Surgery, Wroclaw Medical University, Poland.
Adv Clin Exp Med. 2018 Sep;27(9):1173-1179. doi: 10.17219/acem/69246.
Zirconium - a bioinert metal - in comparison with titanium implants, offers a variety of potential advantages for use in the esthetic area of dentistry due to its tooth-like color. Zirconium dental implants are considered to be an alternative method of treatment to conventional titanium dental implants for patients with a thin gingival biotype.
This study was designed to study the bone tissue response to new zirconia implants with modified surfaces in comparison with commercially available titanium dental implants and commercially available zirconia implants.
The study was carried out on a group of 12 16-month-old minipigs. New zirconia implants with 3 different surfaces were used: M1 - blasted surface, M2 - etched surface and M3 - blasted and etched surface (Maxon Motor GmbH, Sexau, Germany) and compared to conventional titanium implants with an sandblasted and acid etched (SLA) surface (Straumann GmbH, Freiburg, Germany) and commercially available zirconia implants (Ziterion GmbH, Uffenheim, Germany). Histological and micro-computed tomopgraphy (micro-CT) evaluation was performed.
In the micro-CT assessment, the average bone-implant contact (BIC) of the zirconia experimental implants was 41.44%. In particular, the BIC% for M1 was 39.72%, for M2 it was 43.97%, and for M3 - 40.63%; in the control group it was 49.63% and 27.77% for ceramic and titanium control implants, respectively. The intra-group analysis showed no statistically important differences between the BIC values for implants in any group. However, the analysis of BIC for different regions of the same implant showed statistically significant differences in all of the groups between the results of the threaded region and the neck and the apex.
The results of our study suggest that zirconia implants with modified surfaces display features of osseointegration similar to those of titanium implants. These results are promising in using zirconia implants for dental applications in the future.
锆——一种生物惰性金属——与钛植入物相比，因其牙齿般的颜色，在牙科美学领域的应用具有多种潜在优势。对于牙龈生物型薄的患者，锆牙种植体被认为是传统钛牙种植体的一种替代治疗方法。
本研究旨在研究新型表面改性氧化锆种植体与市售钛牙种植体和市售氧化锆种植体相比，其骨组织反应情况。
该研究在一组12只16月龄的小型猪身上进行。使用了3种具有不同表面的新型氧化锆种植体：M1——喷砂表面，M2——蚀刻表面，M3——喷砂和蚀刻表面（德国马克森电机有限公司，塞绍），并与具有喷砂和酸蚀（SLA）表面的传统钛种植体（德国施特拉曼有限公司，弗赖堡）以及市售氧化锆种植体（德国乌芬海姆齐泰里翁有限公司）进行比较。进行了组织学和显微计算机断层扫描（显微CT）评估。
在显微CT评估中，氧化锆实验种植体的平均骨-种植体接触率（BIC）为41.44%。具体而言，M1的BIC%为39.72%，M2为43.97%，M3为40.63%；对照组中，陶瓷对照种植体和钛对照种植体的BIC分别为49.63%和27.77%。组内分析显示，任何一组种植体的BIC值之间均无统计学上的显著差异。然而，对同一种植体不同区域的BIC分析显示，所有组中螺纹区域与颈部及根尖部的结果之间存在统计学上的显著差异。
我们的研究结果表明，表面改性的氧化锆种植体显示出与钛种植体相似的骨结合特征。这些结果为未来氧化锆种植体在牙科应用中的使用带来了希望。
