捕获-再捕获和抗结核药物处方，西班牙巴利阿里群岛，2010-2012 年。

Capture-recapture and anti-tuberculosis drug prescriptions, Balearic Islands, Spain, 2010-2012.

机构信息

Epidemiology Service, Public Health Directorate of the Balearic Islands Regional Government, Palma, Institut d'Investigació Sanitaria de les Illes Balears (IdISBA), Palma.

Epidemiology Service, Public Health Directorate of the Balearic Islands Regional Government, Palma.

出版信息

Int J Tuberc Lung Dis. 2018 Jul 1;22(7):754-759. doi: 10.5588/ijtld.17.0303.

DOI:10.5588/ijtld.17.0303

PMID:29914600

Abstract

SETTING

Tuberculosis (TB) control requires accurate knowledge of TB incidence, but few studies have been published on TB incidence using individual data from drug prescriptions.

OBJECTIVE

To measure the estimated completeness of regional surveillance system data before and after adding data from anti-tuberculosis drug prescriptions.

DESIGN

We compiled data on all individuals who received specific anti-tuberculosis drugs from three sources-the passive surveillance system, the active surveillance system and the anti-tuberculosis drug prescription database-in the Balearic Islands, Spain, between 2010 and 2012. We applied the capture-recapture method to measure completeness of data reporting. Statistical significance was set at P < 0.05, and 95% confidence intervals (CIs) were calculated.

RESULTS

We detected 605 incident cases, compared with an estimated incidence of 719 cases (95%CI 646-793), representing 84.1% data completeness. We detected 480 of an estimated 559 pulmonary TB cases (95%CI 501-617; 85.9% data completeness) and 125 of an estimated 161 extra-pulmonary TB cases (95%CI 113-211; 77.6% data completeness).

CONCLUSIONS

By adding a new source, we increased detection with respect to a previous study by 10.4% for all forms of TB, 9.7% for pulmonary TB and 13% for extra-pulmonary TB.

摘要

背景

结核病（TB）控制需要准确了解结核病的发病率，但使用来自药物处方的个体数据发表的结核病发病率研究甚少。

目的

在增加抗结核药物处方数据前后，衡量区域监测系统数据的估计完整性。

设计

我们汇编了西班牙巴利阿里群岛 2010 年至 2012 年期间三个来源（被动监测系统、主动监测系统和抗结核药物处方数据库）中所有接受特定抗结核药物的个体的数据。我们应用捕获-再捕获方法来衡量数据报告的完整性。统计显著性设为 P<0.05，并计算了 95%置信区间（CI）。

结果

我们检测到 605 例发病病例，而估计的发病率为 719 例（95%CI 646-793），表示数据完整性为 84.1%。我们检测到估计的 559 例肺结核病例中的 480 例（95%CI 501-617；85.9%的数据完整性）和估计的 161 例肺外结核病例中的 125 例（95%CI 113-211；77.6%的数据完整性）。