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鼻气道阻塞的医学治疗。

Medical Treatment of Nasal Airway Obstruction.

作者信息

Cox Daniel R, Wise Sarah K

机构信息

Department of Otolaryngology-Head and Neck Surgery, Emory University, 550 Peachtree Street, MOT 11th Floor, Atlanta, GA 30308, USA.

Department of Otolaryngology-Head and Neck Surgery, Emory University, 550 Peachtree Street, MOT 11th Floor, Atlanta, GA 30308, USA.

出版信息

Otolaryngol Clin North Am. 2018 Oct;51(5):897-908. doi: 10.1016/j.otc.2018.05.004. Epub 2018 Jun 18.

DOI:10.1016/j.otc.2018.05.004
PMID:29914725
Abstract

Nasal obstruction is a common, and potentially debilitating, problem. It is caused by a combination of structural factors and/or mucosal swelling/inflammation. The medical treatment of nasal obstruction is aimed at decreasing mucosal inflammation and edema and is generally guided by the underlying cause. Several different drug classes are commonly used in the treatment of nasal obstruction, each with different indications, and pros and cons to their use. This article discusses the most commonly used therapies for nasal obstruction. Current evidence on the efficacy and side effect profile of each therapy is reviewed.

摘要

鼻塞是一个常见且可能使人衰弱的问题。它由结构因素和/或黏膜肿胀/炎症共同引起。鼻塞的药物治疗旨在减轻黏膜炎症和水肿,通常根据潜在病因进行指导。几种不同类型的药物常用于治疗鼻塞,每种药物都有不同的适应证以及使用的利弊。本文讨论了鼻塞最常用的治疗方法。对每种治疗方法的疗效和副作用方面的现有证据进行了综述。

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Medical Treatment of Nasal Airway Obstruction.鼻气道阻塞的医学治疗。
Otolaryngol Clin North Am. 2018 Oct;51(5):897-908. doi: 10.1016/j.otc.2018.05.004. Epub 2018 Jun 18.
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Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.长期使用羟甲唑啉和赛洛唑啉鼻喷雾剂会引起反跳性肿胀、耐受性和鼻高反应性。
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Efficacy and safety of an oral formulation of cetirizine and prolonged-release pseudoephedrine versus xylometazoline nasal spray in nasal congestion.西替利嗪和缓释伪麻黄碱口服制剂与赛洛唑啉鼻喷雾剂治疗鼻充血的疗效和安全性比较
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引用本文的文献

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Temperature-Controlled Radiofrequency Treatment of the Nasal Valve in Patients With Nasal Obstruction: Long-Term Outcomes.温度控制射频治疗鼻塞患者鼻瓣膜:长期疗效
Otolaryngol Head Neck Surg. 2025 Apr;172(4):1214-1223. doi: 10.1002/ohn.1118. Epub 2025 Jan 17.
2
Topical Anesthesia Versus Submucosal Injection for Radiofrequency Turbinoplasty: Same Benefit but without Patient's Pain. A Comparative Study.用于射频鼻甲成形术的局部麻醉与黏膜下注射:疗效相同但无患者疼痛。一项比较研究。
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):3831-3839. doi: 10.1007/s12070-024-04716-6. Epub 2024 May 20.
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The Prevalence of the Nasal Vestibular Body in Patients With Nasal Obstruction.
鼻阻塞患者鼻前庭体的患病率
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Immunomodulatory agents for COVID-19 treatment: possible mechanism of action and immunopathology features.COVID-19 治疗的免疫调节剂:可能的作用机制和免疫病理学特征。
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