Corey L
J Reprod Med. 1985 Mar;30(3 Suppl):262-8.
Genital herpes simplex virus (HSV) infections have increased markedly in the last ten years. The clinical distinction between HSV and other infectious and noninfectious causes of genital ulcer can be difficult. As such, laboratory confirmation of HSV infection should be used for all women who present with ulcerative or clinically atypical genital lesions. Isolation of the virus in tissue culture remains the gold standard for the laboratory diagnosis of HSV infections. However, many new diagnostic methods of detecting HSV antigens in clinical specimens have been developed. Those procedures appear most useful in specimens taken from genital lesions, and at present they are unproven as reliable methods of obstetric management. Serologic methods can be useful in detecting past HSV infection; however, serodiagnosis is a less sensitive and timely procedure in patients with acute HSV infection.
在过去十年中，单纯疱疹病毒（HSV）引起的生殖器感染显著增加。HSV与其他导致生殖器溃疡的感染性和非感染性病因之间的临床鉴别可能存在困难。因此，对于所有出现溃疡性或临床非典型生殖器病变的女性，均应通过实验室检查来确诊HSV感染。通过组织培养分离病毒仍然是HSV感染实验室诊断的金标准。然而，目前已经开发出许多用于检测临床标本中HSV抗原的新诊断方法。这些方法在取自生殖器病变的标本中似乎最为有用，但目前尚未被证实是可靠的产科管理方法。血清学方法可用于检测既往HSV感染；然而，对于急性HSV感染患者，血清学诊断是一种敏感性较低且及时性较差的检查方法。
